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肺动脉高压的体外生命支持:实践要点

Extracorporeal Life Support in Pulmonary Hypertension: Practical Aspects.

作者信息

Hoeper Marius M

机构信息

Department of Respiratory Medicine, Hannover Medical School, Hannover, Germany.

German Center for Lung Research (DZL), Member of the European Reference Network on Rare Pulmonary Diseases (ERN-LUNG), Hannover, Germany.

出版信息

Semin Respir Crit Care Med. 2023 Dec;44(6):771-776. doi: 10.1055/s-0043-1772752. Epub 2023 Sep 14.

Abstract

Extracorporeal life support (ECLS), in particular veno-arterial extracorporeal membrane oxygenation, has emerged as a potentially life-saving treatment modality in patients presenting with pulmonary hypertension and right heart failure refractory to conventional treatment. Used mainly as a bridge to lung transplantation, ECLS is also being used occasionally as a bridge to recovery in patients with treatable causes of right heart failure. This review article describes indications, contraindications, techniques, and outcomes of the use of ECLS in patients with PH, focusing on practical aspects in the management of such patients.

摘要

体外生命支持(ECLS),尤其是静脉-动脉体外膜肺氧合,已成为治疗肺动脉高压和常规治疗无效的右心衰竭患者的一种潜在的挽救生命的治疗方式。ECLS主要用作肺移植的桥梁,偶尔也用于有可治疗病因的右心衰竭患者作为恢复的桥梁。这篇综述文章描述了ECLS在肺动脉高压患者中的应用指征、禁忌证、技术和结果,重点关注此类患者管理中的实际问题。

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