哮喘儿童血清免疫球蛋白E、针对屋尘和螨虫的皮肤及放射变应原吸附试验

Serum IgE, skin and radioallergosorbent tests for house dust and mites in asthmatic children.

作者信息

Tang R B, Chang H N, Lin F M, Chang Y F, Chou N S, Lin C Y

出版信息

J Asthma. 1986;23(5):245-9. doi: 10.3109/02770908609073168.

Abstract

Thirty asthmatic children were given an intradermal skin test, total IgE measurements and the radioallergosorbent test (RAST) against house dust and house dust mites (Dermatophagoides pteronyssinus and Dermatophagoides farinae). Results of the intradermal skin test and RAST were highly positive with overall agreement in 95.6%. The correlation coefficient between the total IgE and the RAST to house dust was 0.35 (p less than 0.05). There was no significant difference between the total IgE and the RAST to D. pteronyssinus and D. farinae (p greater than 0.05). The highly significant correlation coefficient between house dust and house dust mites (D. farinae, p less than 0.0001; D. pteronyssinus, p less than 0.00001) was determined by RAST. House dust has been found to be the most important allergen in children in Taiwan. The role of mites as a possible allergen in house dust also showed a highly significant correlation in our study.

摘要

对30名哮喘儿童进行了皮内皮肤试验、总IgE测量以及针对屋尘和屋尘螨（粉尘螨和户尘螨）的放射变应原吸附试验（RAST）。皮内皮肤试验和RAST的结果呈高度阳性，总体一致性为95.6%。总IgE与针对屋尘的RAST之间的相关系数为0.35（p<0.05）。针对粉尘螨和户尘螨的总IgE与RAST之间无显著差异（p>0.05）。通过RAST确定，屋尘与屋尘螨之间存在高度显著的相关系数（粉尘螨，p<0.0001；户尘螨，p<0.00001）。已发现屋尘是台湾儿童最重要的变应原。在我们的研究中，螨作为屋尘中可能的变应原的作用也显示出高度显著的相关性。