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住院美沙酮入组:一种为阿片类药物使用障碍的脆弱患者从医院到阿片类药物治疗项目进行衔接的新方案。

In-Hospital Methadone Enrollment: a Novel Program to Facilitate Linkage from the Hospital to the Opioid Treatment Program for Vulnerable Patients with Opioid Use Disorder.

机构信息

Division of Hospital Medicine, Department of Medicine, University of Colorado, Aurora, CO, USA.

Division of General Internal Medicine, University of Colorado, Aurora, CO, USA.

出版信息

J Gen Intern Med. 2024 Feb;39(3):385-392. doi: 10.1007/s11606-023-08411-0. Epub 2023 Sep 15.

DOI:10.1007/s11606-023-08411-0
PMID:37715094
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10897082/
Abstract

INTRODUCTION

Methadone ameliorates opioid withdrawal among hospitalized patients with opioid use disorder (OUD). To continue methadone after hospital discharge, patients must enroll in an opioid treatment program (OTP) per federal regulations. Uncontrolled opioid withdrawal is a barrier to linkage from hospital to OTP.

AIM

Describe a federally compliant In-Hospital Methadone Enrollment Team (IN-MEET) that enrolls hospitalized patients with OUD into an OTP with facilitated hospital to OTP linkage.

SETTING

Seven hundred-bed university hospital in Aurora, CO.

PROGRAM DESCRIPTION

A physician dually affiliated with a hospital's addiction consultation service and a community OTP completes an in-hospital, face-to-face medical assessment required by federal law and titrates methadone to comfort. An OTP-affiliated nurse with hospital privileges completes a psychosocial evaluation and provides case management by arranging transportation and providing weekly telephone check-ins.

PROGRAM EVALUATION METRICS

IN-MEET enrollments completed, hospital to OTP linkage, and descriptive characteristics of patients who completed IN-MEET enrollments compared to patients who completed community OTP enrollments.

RESULTS

Between April 2019 and April 2023, our team completed 165 IN-MEET enrollments. Among a subset of 73 IN-MEET patients, 56 (76.7%) presented to the OTP following hospital discharge. Compared to community OTP enrolled patients (n = 1687), a higher percentage of IN-MEET patients were older (39.7 years, standard deviation [SD] 11.2 years vs. 36.1 years, SD 10.6 years) and were unhoused (n = 43, 58.9% vs. n = 199, 11.8%). Compared to community OTP enrolled patients, a higher percentage of IN-MEET patients reported heroin or fentanyl as their primary substance (n = 53, 72.6% vs. n = 677, 40.1%), reported methamphetamine as their secondary substance (n = 27, 37.0% vs. n = 380, 22.5%), and reported they injected their primary substance (n = 46, 63.0% vs. n = 478, 28.3%).

CONCLUSION

IN-MEET facilitates hospital to OTP linkage among a vulnerable population. This model has the potential to improve methadone access for hospitalized patients who may not otherwise seek out treatment.

摘要

简介

美沙酮可改善患有阿片类药物使用障碍(OUD)的住院患者的阿片类药物戒断症状。根据联邦法规,为了在出院后继续使用美沙酮,患者必须参加阿片类药物治疗计划(OTP)。未得到控制的阿片类药物戒断是将患者从医院转到 OTP 的障碍。

目的

描述一个符合联邦规定的住院美沙酮注册团队(IN-MEET),该团队通过促进医院与 OTP 的联系,将患有 OUD 的住院患者纳入 OTP 治疗。

地点

科罗拉多州奥罗拉市的一家拥有 700 张床位的大学医院。

项目描述

一名医生同时隶属于医院的成瘾咨询服务和社区 OTP,完成联邦法律要求的住院面对面医疗评估,并滴定美沙酮以达到舒适状态。一名拥有医院特权的 OTP 附属护士完成心理社会评估,并通过安排交通和提供每周电话检查来提供病例管理。

项目评估指标

IN-MEET 完成注册、医院到 OTP 的衔接情况,以及与完成社区 OTP 注册的患者相比,完成 IN-MEET 注册的患者的描述性特征。

结果

在 2019 年 4 月至 2023 年 4 月期间,我们的团队完成了 165 次 IN-MEET 注册。在 73 名 IN-MEET 患者的一个子集中,有 56 名(76.7%)在出院后到 OTP 就诊。与社区 OTP 注册患者(n=1687)相比,IN-MEET 患者中有更高比例的人年龄较大(39.7 岁,标准差[SD]为 11.2 岁 vs. 36.1 岁,SD 为 10.6 岁)和无家可归(n=43,58.9% vs. n=199,11.8%)。与社区 OTP 注册患者相比,IN-MEET 患者中有更高比例的人报告海洛因或芬太尼是他们的主要物质(n=53,72.6% vs. n=677,40.1%),报告他们的次要物质是冰毒(n=27,37.0% vs. n=380,22.5%),并报告他们注射了主要物质(n=46,63.0% vs. n=478,28.3%)。

结论

IN-MEET 促进了弱势人群的医院与 OTP 的衔接。这种模式有可能改善可能不会寻求治疗的住院患者获得美沙酮的机会。

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Things We Do for No Reason™: Avoiding methadone for opioid withdrawal.我们无端做的事™:避免使用美沙酮进行阿片类药物戒断。
J Hosp Med. 2023 Nov;18(11):1034-1037. doi: 10.1002/jhm.13138. Epub 2023 May 27.
2
Predictors of Linkage to an Opioid Treatment Program and Methadone Treatment Retention following Hospital Discharge in a Safety-Net Setting.在安全网环境下,出院后与阿片类药物治疗计划和美沙酮治疗保持联系的预测因素。
Subst Use Misuse. 2023;58(9):1172-1176. doi: 10.1080/10826084.2023.2212070. Epub 2023 May 17.
3
Association of Early Opioid Withdrawal Treatment Strategy and Patient-Directed Discharge Among Hospitalized Patients with Opioid Use Disorder.早期阿片类药物戒断治疗策略与住院阿片类药物使用障碍患者患者导向出院的关联。
J Gen Intern Med. 2023 Aug;38(10):2289-2297. doi: 10.1007/s11606-023-08059-w. Epub 2023 Feb 14.
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Identifying factors that contribute to burnout and resilience among hospital-based addiction medicine providers: A qualitative study.确定导致医院成瘾医学提供者出现倦怠和适应力的因素:一项定性研究。
J Subst Abuse Treat. 2023 Jan;144:108924. doi: 10.1016/j.jsat.2022.108924. Epub 2022 Oct 26.
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Association of Methamphetamine and Opioid Use With Nonfatal Overdose in Rural Communities.农村地区冰毒和阿片类药物使用与非致命性药物过量的关联。
JAMA Netw Open. 2022 Aug 1;5(8):e2226544. doi: 10.1001/jamanetworkopen.2022.26544.
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Management of opioid use disorder, opioid withdrawal, and opioid overdose prevention in hospitalized adults: A systematic review of existing guidelines.成人住院患者阿片类药物使用障碍、阿片类药物戒断和阿片类药物过量预防的管理:现有指南的系统评价。
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