Section of Palliative Care, Division of General Internal Medicine, Duke University School of Medicine, Durham, NC.
Division of Palliative Care and Geriatric Medicine, Massachusetts General Hospital, Boston, MA.
Curr Probl Cancer. 2023 Oct;47(5):101011. doi: 10.1016/j.currproblcancer.2023.101011. Epub 2023 Sep 6.
Specialist palliative care provides additional support to facilitate living well with a serious illness, like cancer, even while pursuing disease-directed therapy. For patients with hematologic malignancies, integrated specialist palliative care improves symptom burden, mood, and quality of life, with benefits even extending to caregivers. Despite this, patients with hematologic malignancies continue to have significant unmet palliative care needs and typically access palliative care late in their disease trajectories, if at all. In this paper, we will define specialist palliative care and review its benefits for patients with hematologic malignancies. We will discuss the unmet palliative care needs of this patient population and the barriers to integrating palliative care and oncologic care. Finally, we will explore innovations and areas of future research to enhance and optimize palliative care integration into usual cancer care treatment for patients with hematologic malignancies. We will explore the importance of ongoing clinical trials that are examining the correct "dose" of palliative care; the use of technology and telehealth; and the use of novel treatments for this patient population. Together, we will consider innovative avenues to provide palliative care to patients with hematologic malignancies and their caregivers.
专科姑息治疗为患有癌症等严重疾病的患者提供额外的支持，以帮助他们在接受疾病导向治疗的同时，更好地生活。对于血液恶性肿瘤患者，综合专科姑息治疗可改善症状负担、情绪和生活质量，甚至使护理人员受益。尽管如此，血液恶性肿瘤患者仍存在显著的未满足的姑息治疗需求，且通常在疾病进程中晚期才开始接受姑息治疗，如果有的话。在本文中，我们将定义专科姑息治疗，并回顾其对血液恶性肿瘤患者的益处。我们将讨论该患者群体未满足的姑息治疗需求，以及整合姑息治疗和肿瘤治疗的障碍。最后，我们将探讨创新和未来研究领域，以加强和优化血液恶性肿瘤患者姑息治疗融入常规癌症治疗。我们将探讨正在进行的临床试验的重要性，这些试验正在研究姑息治疗的正确“剂量”；技术和远程医疗的使用；以及为该患者群体使用新的治疗方法。我们将共同探讨为血液恶性肿瘤患者及其护理人员提供姑息治疗的创新途径。
