• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

黑骨病：膝关节置换术中发现的褐黄病性关节炎

Black Bone Disease: Ochronotic Arthritis Detected during Knee Arthroplasty.

作者信息

Kang Ho Won, Kim Minsub, Oh Jin-Young, Youn Changhyun

机构信息

Department of Orthopedic Surgery, Ewha Womans University, College of Medicine, Mokdong Hospital, Seoul, Korea.

Department of Orthopedic Surgery, Ulsan Hospital, Ulsan, Korea.

出版信息

J Bone Metab. 2023 Aug;30(3):283-287. doi: 10.11005/jbm.2023.30.3.283. Epub 2023 Aug 31.

DOI:10.11005/jbm.2023.30.3.283
PMID:37718906
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10509029/
Abstract

Alkaptonuria is an extremely rare autosomal recessive metabolic disorder characterized by dark urine, ochronosis, and arthritis of the spine and major joints. We report a case of ochronotic arthritis observed during total knee replacement surgery in a 65-year-old male patient with no relevant medical history. Based on a literature review, this is the first case of ochronotic arthritis reported in Korea.

摘要

黑尿症是一种极其罕见的常染色体隐性代谢紊乱疾病，其特征为尿液变黑、褐黄病以及脊柱和主要关节的关节炎。我们报告了一例在全膝关节置换手术中观察到的褐黄病性关节炎病例，该患者为一名65岁男性，无相关病史。根据文献综述，这是韩国报告的首例褐黄病性关节炎病例。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/272f/10509029/9e903f102018/jbm-2023-30-3-283f6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/272f/10509029/462f62f1919e/jbm-2023-30-3-283f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/272f/10509029/cc42a14dc384/jbm-2023-30-3-283f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/272f/10509029/bcc6dd95084e/jbm-2023-30-3-283f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/272f/10509029/4a75e6e41d1b/jbm-2023-30-3-283f4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/272f/10509029/9403b108aad7/jbm-2023-30-3-283f5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/272f/10509029/9e903f102018/jbm-2023-30-3-283f6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/272f/10509029/462f62f1919e/jbm-2023-30-3-283f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/272f/10509029/cc42a14dc384/jbm-2023-30-3-283f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/272f/10509029/bcc6dd95084e/jbm-2023-30-3-283f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/272f/10509029/4a75e6e41d1b/jbm-2023-30-3-283f4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/272f/10509029/9403b108aad7/jbm-2023-30-3-283f5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/272f/10509029/9e903f102018/jbm-2023-30-3-283f6.jpg

相似文献

1
Black Bone Disease: Ochronotic Arthritis Detected during Knee Arthroplasty.黑骨病：膝关节置换术中发现的褐黄病性关节炎
J Bone Metab. 2023 Aug;30(3):283-287. doi: 10.11005/jbm.2023.30.3.283. Epub 2023 Aug 31.
2
A rare cause of arthropathy: An ochronotic patient with black joints.一种罕见的关节病病因：一位患有黑关节的褐黄病患者。
Int J Surg Case Rep. 2014;5(8):554-7. doi: 10.1016/j.ijscr.2014.06.015. Epub 2014 Jun 27.
3
Ochronotic arthritis and ochronotic Achilles tendon rupture in alkaptonuria: A 6 years follow-up case report in China.尿黑酸尿症中的褐黄病性关节炎和褐黄病性跟腱断裂：中国1例6年随访病例报告
Medicine (Baltimore). 2019 Aug;98(34):e16837. doi: 10.1097/MD.0000000000016837.
4
Ochronotic Surprise during Total Knee Replacement! A Case Report.全膝关节置换术中的褐黄病意外！一例报告。
J Orthop Case Rep. 2021 Oct;11(10):49-52. doi: 10.13107/jocr.2021.v11.i10.2464.
5
Arthroplasty in Ochronotic Arthropathy: 3 Replacements in a Single Patient with a Long-term Follow-up of 11 Years.褐黄病性关节病的关节置换术：1例患者的3次置换及11年长期随访
J Orthop Case Rep. 2024 Feb;14(2):76-81. doi: 10.13107/jocr.2024.v14.i02.4224.
6
ARTHROPLASTY IN ALKAPTONURIC OCHRONOSIS.黑尿病性褐黄病的关节成形术
J Popul Ther Clin Pharmacol. 2019 Jul 26;26(2):e20-e24. doi: 10.15586/jptcp.v26i2.624.
7
Bilateral hip and knee arthroplasty in ochronotic arthritis.褐黄病性关节炎的双侧髋关节和膝关节置换术。
J Indian Med Assoc. 2014 Feb;112(2):124-6.
8
Cementless total knee arthroplasty in ochronotic arthropathy: a case report with a 4-year follow-up.褐黄病性关节病的非骨水泥型全膝关节置换术：一例4年随访的病例报告
J Arthroplasty. 2000 Jun;15(4):539-43. doi: 10.1054/arth.2000.4228.
9
Degenerative arthritis of the knee secondary to ochronosis.褐黄病继发的膝关节退行性关节炎
Bull NYU Hosp Jt Dis. 2011;69(4):331-4.
10
Ochronotic arthritis: case reports and review of the literature.褐黄病性关节炎：病例报告及文献综述
Rheumatol Int. 2005 Aug;25(6):465-8. doi: 10.1007/s00296-004-0538-x. Epub 2004 Dec 3.

本文引用的文献

1
Alkaptonuria - Past, present and future.尿黑酸尿症——过去、现在和未来。
Adv Clin Chem. 2023;114:47-81. doi: 10.1016/bs.acc.2023.02.005. Epub 2023 Mar 28.
2
LIM Homeobox Transcription Factor 1-β Expression is Upregulated in Patients with Osteolysis after Total Ankle Arthroplasty and Inhibits Receptor Activator of Nuclear Factor-κB Ligand-Induced Osteoclast Differentiation in Vitro.LIM 同源框转录因子 1-β 在全踝关节置换术后骨溶解患者中表达上调，并在体外抑制核因子-κB 受体激活剂配体诱导的破骨细胞分化。
J Bone Metab. 2022 Aug;29(3):165-174. doi: 10.11005/jbm.2022.29.3.165. Epub 2022 Aug 31.
3
Blue man: Ochronosis in Otolaryngology.
蓝色人种：耳鼻喉科的褐黄病
Clin Case Rep. 2022 Apr 15;10(4):e05717. doi: 10.1002/ccr3.5717. eCollection 2022 Apr.
4
Clinical and Surgical Insights on Bilateral Total Knee Arthroplasty in Ochronotic Arthropathy: A Case-based Review.褐黄病性关节病双侧全膝关节置换术的临床与外科见解：基于病例的综述
J Orthop Case Rep. 2021 Dec;11(12):30-34. doi: 10.13107/jocr.2021.v11.i12.2554.
5
Alkaptonuria with rapidly destructive arthropathy of the hip: A case report and literature review.尿黑酸尿症伴髋关节进行性破坏性关节炎：病例报告及文献复习。
Acta Orthop Traumatol Turc. 2021 Dec;55(6):563-568. doi: 10.5152/j.aott.2021.21205.
6
Intraoperative Diagnosis of a Rare Case of Arthropathy - A Case Report and Review of Literature.罕见关节病的术中诊断——病例报告及文献综述
J Orthop Case Rep. 2020 Nov;10(8):58-62. doi: 10.13107/jocr.2020.v10.i08.1860.
7
Clinical and radiological outcomes of total joint arthroplasty in patients with ochronotic arthropathy.奥克洛诺osis 关节炎患者全关节置换术的临床和影像学结果。
Eur J Orthop Surg Traumatol. 2020 Jul;30(5):923-929. doi: 10.1007/s00590-020-02651-0. Epub 2020 Mar 14.
8
Calcaneal Avulsion of an Ochronotic Achilles Tendon: A Case Report.褐黄病性跟腱跟骨撕脱：一例报告
J Foot Ankle Surg. 2018 Jan-Feb;57(1):179-183. doi: 10.1053/j.jfas.2017.07.012. Epub 2017 Nov 4.
9
Interferences of homogentisic acid (HGA) on routine clinical chemistry assays in serum and urine and the implications for biochemical monitoring of patients with alkaptonuria.尿黑酸（HGA）对血清和尿液中常规临床化学检测的干扰以及对尿黑酸尿症患者生化监测的影响。
Clin Biochem. 2014 May;47(7-8):640-7. doi: 10.1016/j.clinbiochem.2013.12.016. Epub 2013 Dec 27.
10
New developments in ochronosis: review of the literature.褐黄病的新进展：文献综述
Rheumatol Int. 2005 Mar;25(2):81-5. doi: 10.1007/s00296-004-0498-1. Epub 2004 Aug 21.