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垂体卒中作为新型冠状病毒肺炎感染的一种并发症

Pituitary Apoplexy as a Complication of COVID-19 Infection.

作者信息

Hussain Hassan, Janaka Kvc, Muthukuda D T, Perera S G

机构信息

General Medicine, Sri Jayewardenepura General Hospital, Colombo, LKA.

Internal Medicine, Sri Jayewardenepura General Hospital, Colombo, LKA.

出版信息

Cureus. 2023 Aug 15;15(8):e43524. doi: 10.7759/cureus.43524. eCollection 2023 Aug.

DOI:10.7759/cureus.43524
PMID:37719628
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10500954/
Abstract

Pituitary apoplexy (PA) is a complication occurring due to hemorrhage and/or infarction in a pituitary adenoma due to various pathophysiological mechanisms. Herein, we report a case of a 47-year-old previously healthy male who presented with fever and reduced level of consciousness for one day. During the hospital stay, he was diagnosed with PA in a background of pituitary macroadenoma along with positive nasopharyngeal swabs for SARS-CoV-2 infection. Even though the PA was successfully managed, the patient succumbed four days after admission due to respiratory failure caused by severe COVID-19 pneumonia.

摘要

垂体卒中（PA）是由于各种病理生理机制导致垂体腺瘤内出血和/或梗死而发生的一种并发症。在此，我们报告一例47岁既往健康男性病例，该患者出现发热和意识水平下降1天。住院期间，他在垂体大腺瘤背景下被诊断为垂体卒中，同时鼻咽拭子检测SARS-CoV-2感染呈阳性。尽管垂体卒中得到了成功处理，但患者在入院4天后因严重COVID-19肺炎导致呼吸衰竭而死亡。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f50a/10500954/e07a94c161ea/cureus-0015-00000043524-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f50a/10500954/e07a94c161ea/cureus-0015-00000043524-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f50a/10500954/e07a94c161ea/cureus-0015-00000043524-i01.jpg

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Endocrine. 2025 Feb;87(2):459-467. doi: 10.1007/s12020-024-04078-7. Epub 2024 Oct 21.
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本文引用的文献

1
Pituitary ​​​​Apoplexy​​ With Pituitary Macroadenoma in a Patient With ​​Asymptomatic ​​​COVID-19: ​​A Case ​​​Report.一名无症状新冠病毒肺炎患者合并垂体大腺瘤的垂体卒中：病例报告
Cureus. 2022 Dec 22;14(12):e32810. doi: 10.7759/cureus.32810. eCollection 2022 Dec.
2
Rapidly Progressive Pituitary Apoplexy in a Patient with COVID-19 Disease Treated with Endoscopic Endonasal Surgery.一名接受内镜鼻内手术治疗的新冠肺炎患者发生快速进展性垂体卒中。
J Neurol Surg Rep. 2022 Jan 10;83(1):e8-e12. doi: 10.1055/s-0041-1742104. eCollection 2022 Jan.
3
Coronavirus disease 2019 infection and pituitary apoplexy: A causal relation or just a coincidence? A case report and review of the literature.
一名新冠病毒检测呈阳性患者的脑动静脉畸形出血与垂体腺瘤
Cureus. 2024 Aug 23;16(8):e67644. doi: 10.7759/cureus.67644. eCollection 2024 Aug.
2019冠状病毒病感染与垂体卒中：因果关系还是纯属巧合？一例病例报告及文献综述
Surg Neurol Int. 2021 Jun 28;12:317. doi: 10.25259/SNI_401_2021. eCollection 2021.
4
A Rare Case of SARS-CoV-2 Infection Associated With Pituitary Apoplexy Without Comorbidities.一例罕见的新型冠状病毒肺炎感染合并垂体卒中且无合并症病例。
J Endocr Soc. 2021 Jan 2;5(3):bvaa203. doi: 10.1210/jendso/bvaa203. eCollection 2021 Mar 1.
5
Pituitary apoplexy associated with acute COVID-19 infection and pregnancy.与急性 COVID-19 感染和妊娠相关的垂体卒中。
Pituitary. 2020 Dec;23(6):716-720. doi: 10.1007/s11102-020-01080-w. Epub 2020 Sep 11.
6
Pituitary Apoplexy Presenting as Ophthalmoplegia and Altered Level of Consciousness without Headache.以眼肌麻痹和意识水平改变为表现且无头痛的垂体卒中
Case Rep Endocrinol. 2018 May 9;2018:7124364. doi: 10.1155/2018/7124364. eCollection 2018.