• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

相似文献

1
Bilateral Ovarian Metastases of Hepatocellular Carcinoma Diagnosed with F-Fluorocholine PET/CT in a Patient with Endometriosis.在一名子宫内膜异位症患者中，通过F-氟胆碱PET/CT诊断出肝细胞癌的双侧卵巢转移。
Nucl Med Mol Imaging. 2023 Oct;57(5):251-253. doi: 10.1007/s13139-023-00796-4. Epub 2023 Apr 14.
2
Positron emission tomography/computed tomography with 18F-fluorocholine improve tumor staging and treatment allocation in patients with hepatocellular carcinoma.正电子发射断层扫描/计算机断层扫描联合 18F-氟代胆碱可改善肝细胞癌患者的肿瘤分期和治疗分配。
J Hepatol. 2018 Aug;69(2):336-344. doi: 10.1016/j.jhep.2018.02.018. Epub 2018 Mar 6.
3
Arterial Phase 18F-Fluorocholine PET/CT in Hepatocellular Carcinoma.动脉期 18F-氟代胆碱 PET/CT 在肝细胞癌中的应用。
Clin Nucl Med. 2019 Feb;44(2):133-136. doi: 10.1097/RLU.0000000000002397.
4
Metabolic characteristics distinguishing intrahepatic cholangiocarcinoma: a negative pilot study of (18)F-fluorocholine PET/CT clarified by transcriptomic analysis.区分肝内胆管癌的代谢特征：一项通过转录组分析阐明的(18)F-氟胆碱PET/CT阴性初步研究。
Am J Nucl Med Mol Imaging. 2016 Jan 28;6(1):73-83. eCollection 2016.
5
A pilot comparison of 18F-fluorodeoxyglucose and 18F-fluorocholine PET/CT to predict early recurrence of unifocal hepatocellular carcinoma after surgical resection.18F-氟脱氧葡萄糖与18F-氟胆碱PET/CT预测单灶性肝细胞癌手术切除后早期复发的初步比较
Nucl Med Commun. 2012 Jul;33(7):757-65. doi: 10.1097/MNM.0b013e328350fb9f.
6
Efficacy of contrast-enhanced FDG PET/CT in patients awaiting liver transplantation with rising alpha-fetoprotein after bridge therapy of hepatocellular carcinoma.对比增强 FDG PET/CT 在桥接治疗肝细胞癌后甲胎蛋白升高的肝移植患者中的疗效。
Eur Radiol. 2018 Dec;28(12):5356-5367. doi: 10.1007/s00330-018-5425-z. Epub 2018 Jun 12.
7
Transcriptomics Associates Molecular Features with F-Fluorocholine PET/CT Imaging Phenotype and Its Potential Relationship to Survival in Hepatocellular Carcinoma.转录组学协会将分子特征与 F-氟代胆碱 PET/CT 成像表型及其与肝细胞癌生存的潜在关系联系起来。
Cancer Res. 2019 Apr 1;79(7):1696-1704. doi: 10.1158/0008-5472.CAN-18-3837. Epub 2019 Feb 13.
8
PET/CT in patients with hepatocellular carcinoma using [(18)F]fluorocholine: preliminary comparison with [(18)F]FDG PET/CT.使用[（18）F]氟胆碱的肝细胞癌患者的PET/CT：与[（18）F]FDG PET/CT的初步比较
Eur J Nucl Med Mol Imaging. 2006 Nov;33(11):1285-9. doi: 10.1007/s00259-006-0164-9. Epub 2006 Jun 27.
9
A prospective evaluation of 18F-FDG and 11C-acetate PET/CT for detection of primary and metastatic hepatocellular carcinoma.18F-FDG和11C-醋酸盐PET/CT用于检测原发性和转移性肝细胞癌的前瞻性评估。
J Nucl Med. 2008 Dec;49(12):1912-21. doi: 10.2967/jnumed.108.055087. Epub 2008 Nov 7.
10
Differential Diagnosis of Hepatic Mass with Central Scar: Focal Nodular Hyperplasia Mimicking Fibrolamellar Hepatocellular Carcinoma.伴有中央瘢痕的肝脏肿块的鉴别诊断：酷似纤维板层型肝细胞癌的局灶性结节性增生。
Diagnostics (Basel). 2021 Dec 27;12(1):44. doi: 10.3390/diagnostics12010044.

引用本文的文献

1
Correlation between dual-time-point F-FDG PET/CT imaging and pathological grade in hepatocellular carcinoma.双时间点F-FDG PET/CT成像与肝细胞癌病理分级的相关性
Quant Imaging Med Surg. 2025 Aug 1;15(8):6801-6810. doi: 10.21037/qims-2025-196. Epub 2025 Jul 30.

本文引用的文献

1
Interference of Known or Suspected Endometriosis in Reporting FDG PET/CT Performed in Another Indication.已知或疑似子宫内膜异位症对其他适应证行 FDG PET/CT 检查报告的干扰。
Clin Nucl Med. 2022 Apr 1;47(4):305-313. doi: 10.1097/RLU.0000000000004049.
2
Endometriosis.子宫内膜异位症。
Endocr Rev. 2019 Aug 1;40(4):1048-1079. doi: 10.1210/er.2018-00242.
3
F-Fluorocholine Uptake and Positron Emission Tomography Imaging in Rat Peritoneal Endometriosis.F-氟胆碱摄取与正电子发射断层扫描成像在大鼠腹膜子宫内膜异位症中的应用
Reprod Sci. 2018 Jan;25(1):19-25. doi: 10.1177/1933719117728799. Epub 2017 Sep 6.
4
Diagnostic value of combining ¹¹C-choline and ¹⁸F-FDG PET/CT in hepatocellular carcinoma.¹¹C-胆碱与¹⁸F-FDG PET/CT联合应用在肝细胞癌中的诊断价值
Eur J Nucl Med Mol Imaging. 2016 May;43(5):852-859. doi: 10.1007/s00259-015-3241-0. Epub 2015 Nov 18.
5
Diagnostic role of radiolabelled choline PET or PET/CT in hepatocellular carcinoma: a systematic review and meta-analysis.放射性标记胆碱PET或PET/CT在肝细胞癌中的诊断作用：一项系统评价和荟萃分析
Hepatol Int. 2014 Oct;8(4):493-500. doi: 10.1007/s12072-014-9566-0. Epub 2014 Sep 3.
6
Metastasis of hepatocellular carcinoma to the ovary: a case report and review of the literature.肝细胞癌转移至卵巢：病例报告及文献复习。
Gut Liver. 2011 Dec;5(4):543-7. doi: 10.5009/gnl.2011.5.4.543. Epub 2011 Nov 21.
7
Evaluation of 18FDG PET-CT in the diagnosis of endometriosis: a prospective study.18FDG PET-CT 诊断子宫内膜异位症的评价：一项前瞻性研究。
Reprod Sci. 2011 Jun;18(6):540-4. doi: 10.1177/1933719110392060. Epub 2011 Feb 1.
8
Extrahepatic metastases of hepatocellular carcinoma.肝细胞癌的肝外转移
Radiology. 2000 Sep;216(3):698-703. doi: 10.1148/radiology.216.3.r00se24698.
9
Hepatocellular carcinoma metastatic to the ovary: a case report.肝细胞癌转移至卵巢：一例报告
Am J Obstet Gynecol. 1983 Jul 15;146(6):715-7. doi: 10.1016/0002-9378(83)91020-7.

在一名子宫内膜异位症患者中，通过F-氟胆碱PET/CT诊断出肝细胞癌的双侧卵巢转移。

Bilateral Ovarian Metastases of Hepatocellular Carcinoma Diagnosed with F-Fluorocholine PET/CT in a Patient with Endometriosis.

作者信息

Latgé Adrien, Averous Gerlinde, Gressel Anne, Faitot François, Leroy-Freschini Benjamin

机构信息

Department of Nuclear Medicine & Molecular Imaging, Institut de Cancérologie de Strasbourg Europe (ICANS), Strasbourg, France.

Department of Pathology, Hôpital de Hautepierre, Hôpitaux Universitaires de Strasbourg, Strasbourg, France.

出版信息

Nucl Med Mol Imaging. 2023 Oct;57(5):251-253. doi: 10.1007/s13139-023-00796-4. Epub 2023 Apr 14.

DOI:10.1007/s13139-023-00796-4
PMID:37720883
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10504130/
Abstract

A 47-year-old woman with history of hepatocellular carcinoma was referred for F-fluorocholine PET/CT evaluation due to elevated alpha-fetoprotein. The examination showed several peritoneal uptakes and two nodular pelvic foci. Coelioscopic exploration allowed confirmation and resection of multiple peritoneal metastases from hepatocellular carcinoma while pelvic biopsies revealed endometriosis and endosalpingiosis. However, alpha-fetoprotein kept rising: subsequent F-fluorodesoxyglucose PET/CT exploration found no pelvic uptake, while F-fluorocholine PET/CT revealed intense tracer accumulation in the two pelvic masses corresponding to bilateral ovarian metastases of hepatocellular carcinoma. We highlight the importance of F-fluorocholine PET/CT in hepatocellular carcinoma especially in patients with confounding comorbidities such as endometriosis.

摘要

一名有肝细胞癌病史的47岁女性因甲胎蛋白升高而接受F-氟胆碱PET/CT评估。检查显示有多处腹膜摄取及两个盆腔结节灶。腹腔镜探查证实并切除了肝细胞癌的多处腹膜转移灶，而盆腔活检显示为子宫内膜异位症和输卵管内膜异位症。然而，甲胎蛋白持续升高：随后的F-氟脱氧葡萄糖PET/CT检查未发现盆腔摄取，而F-氟胆碱PET/CT显示在对应于肝细胞癌双侧卵巢转移的两个盆腔肿块中有强烈的示踪剂积聚。我们强调F-氟胆碱PET/CT在肝细胞癌中的重要性，尤其是在患有诸如子宫内膜异位症等混淆合并症的患者中。