在一名子宫内膜异位症患者中，通过F-氟胆碱PET/CT诊断出肝细胞癌的双侧卵巢转移。
Bilateral Ovarian Metastases of Hepatocellular Carcinoma Diagnosed with F-Fluorocholine PET/CT in a Patient with Endometriosis.
作者信息
Latgé Adrien, Averous Gerlinde, Gressel Anne, Faitot François, Leroy-Freschini Benjamin
机构信息
Department of Nuclear Medicine & Molecular Imaging, Institut de Cancérologie de Strasbourg Europe (ICANS), Strasbourg, France.
Department of Pathology, Hôpital de Hautepierre, Hôpitaux Universitaires de Strasbourg, Strasbourg, France.
出版信息
Nucl Med Mol Imaging. 2023 Oct;57(5):251-253. doi: 10.1007/s13139-023-00796-4. Epub 2023 Apr 14.
A 47-year-old woman with history of hepatocellular carcinoma was referred for F-fluorocholine PET/CT evaluation due to elevated alpha-fetoprotein. The examination showed several peritoneal uptakes and two nodular pelvic foci. Coelioscopic exploration allowed confirmation and resection of multiple peritoneal metastases from hepatocellular carcinoma while pelvic biopsies revealed endometriosis and endosalpingiosis. However, alpha-fetoprotein kept rising: subsequent F-fluorodesoxyglucose PET/CT exploration found no pelvic uptake, while F-fluorocholine PET/CT revealed intense tracer accumulation in the two pelvic masses corresponding to bilateral ovarian metastases of hepatocellular carcinoma. We highlight the importance of F-fluorocholine PET/CT in hepatocellular carcinoma especially in patients with confounding comorbidities such as endometriosis.
一名有肝细胞癌病史的47岁女性因甲胎蛋白升高而接受F-氟胆碱PET/CT评估。检查显示有多处腹膜摄取及两个盆腔结节灶。腹腔镜探查证实并切除了肝细胞癌的多处腹膜转移灶，而盆腔活检显示为子宫内膜异位症和输卵管内膜异位症。然而，甲胎蛋白持续升高：随后的F-氟脱氧葡萄糖PET/CT检查未发现盆腔摄取，而F-氟胆碱PET/CT显示在对应于肝细胞癌双侧卵巢转移的两个盆腔肿块中有强烈的示踪剂积聚。我们强调F-氟胆碱PET/CT在肝细胞癌中的重要性，尤其是在患有诸如子宫内膜异位症等混淆合并症的患者中。
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