Suppr超能文献

急性胰腺炎的现代管理:你需要了解的内容。

Contemporary management of acute pancreatitis: What you need to know.

作者信息

Palumbo Rachael, Schuster Kevin M

机构信息

From the Department of Surgery, Yale School of Medicine, New Haven, Connecticut.

出版信息

J Trauma Acute Care Surg. 2024 Jan 1;96(1):156-165. doi: 10.1097/TA.0000000000004143. Epub 2023 Dec 11.

Abstract

Acute pancreatitis and management of its complications is a common consult for the acute care surgeon. With the ongoing development of both operative and endoscopic treatment modalities, management recommendations continue to evolve. We describe the current diagnostic and treatment guidelines for acute pancreatitis through the lens of acute care surgery. Topics, including optimal nutrition, timing of cholecystectomy in gallstone pancreatitis, and the management of peripancreatic fluid collections, are discussed. Although the management severe acute pancreatitis can include advanced interventional modalities including endoscopic, percutaneous, and surgical debridement, the initial management of acute pancreatitis includes fluid resuscitation, early enteral nutrition, and close monitoring with consideration of cross-sectional imaging and antibiotics in the setting of suspected superimposed infection. Several scoring systems including the Revised Atlanta Criteria, the Bedside Index for Severity in Acute Pancreatitis score, and the American Association for the Surgery of Trauma grade have been devised to classify and predict the development of the severe acute pancreatitis. In biliary pancreatitis, cholecystectomy prior to discharge is recommended in mild disease and within 8 weeks of necrotizing pancreatitis, while early peripancreatic fluid collections should be managed without intervention. Underlying infection or ongoing symptoms warrant delayed intervention with technique selection dependent on local expertise, anatomic location of the fluid collection, and the specific clinical scenario. Landmark trials have shifted therapy from maximally invasive necrosectomy to more minimally invasive step-up approaches. The acute care surgeon should maintain a skill set that includes these minimally invasive techniques to successfully manage these patients. Overall, the management of acute pancreatitis for the acute care surgeon requires a strong understanding of both the clinical decisions and the options for intervention should this be necessary.

摘要

急性胰腺炎及其并发症的处理是急性外科医生常见的会诊内容。随着手术和内镜治疗方式的不断发展,管理建议也在持续演变。我们从急性外科的角度描述当前急性胰腺炎的诊断和治疗指南。讨论的主题包括最佳营养、胆石性胰腺炎中胆囊切除术的时机以及胰周液体积聚的处理。尽管重症急性胰腺炎的管理可能包括先进的介入方式,如内镜、经皮和手术清创,但急性胰腺炎的初始管理包括液体复苏、早期肠内营养以及在怀疑有叠加感染时进行横断面成像和使用抗生素的密切监测。已经设计了几种评分系统,包括修订的亚特兰大标准、急性胰腺炎严重程度床边指数评分和美国创伤外科学会分级,以分类和预测重症急性胰腺炎的发展。在胆源性胰腺炎中,轻度疾病建议在出院前进行胆囊切除术,坏死性胰腺炎则在8周内进行,而早期胰周液体积聚应无需干预进行处理。潜在感染或持续症状需要延迟干预,技术选择取决于当地专业知识、液体积聚的解剖位置和具体临床情况。具有里程碑意义的试验已将治疗方法从最大程度的侵入性坏死切除术转变为更微创的逐步升级方法。急性外科医生应掌握包括这些微创技术在内的技能组合,以成功管理这些患者。总体而言,急性外科医生对急性胰腺炎的管理需要深入理解临床决策以及必要时的干预选择。

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验