Department of Basic Medicine, School of Medicine, Shihezi University, Shihezi City, Xinjiang, People's Republic of China.
NHC Key Laboratory of Prevention and Treatment of Central Asia High Incidence Diseases, First Affiliated Hospital, School of Medicine, Shihezi University, Shihezi City, Xinjiang, People's Republic of China.
Vet Clin Pathol. 2023 Dec;52(4):732-736. doi: 10.1111/vcp.13297. Epub 2023 Sep 18.
The Himalayan marmot (Marmota himalayana) plays a reservoir role in the epidemiology of brucellosis. However, the changes in blood biochemical parameters are still unclear in Brucella-seropositive marmots.
The present study was designed to explore the hematologic and biochemical variable changes in Brucella-seropositive marmots.
Blood samples were collected from the dorsalis pedis vein of Himalayan marmots (24 Brucella-seropositive marmots and 24 Brucella-free marmots). Ten hematologic and 10 serum biochemical variable examinations were performed and analyzed.
Our results showed that leukocyte, platelet, neutrophil, and lymphocyte counts significantly increased, while the level of carbon dioxide combining power decreased in Brucella-infected marmots. These findings indicate that Brucella triggers an immune response in Himalayan marmots.
This study provides a preliminary investigation of the changes in blood biochemical analytes in Brucella-infected marmots. The interaction between Brucella infection and blood biochemical indices in Himalayan marmots should be further explored.
喜马拉雅旱獭（Marmota himalayana）在布氏杆菌病的流行病学中起着储存宿主的作用。然而，布氏杆菌血清阳性旱獭的血液生化参数变化仍不清楚。
本研究旨在探讨布氏杆菌血清阳性旱獭的血液学和生化变量变化。
从喜马拉雅旱獭（24 只布氏杆菌血清阳性旱獭和 24 只布氏杆菌阴性旱獭）的跖背静脉采集血液样本。进行了 10 项血液学和 10 项血清生化检查并进行了分析。
我们的结果表明，白细胞、血小板、中性粒细胞和淋巴细胞计数显著增加，而二氧化碳结合力水平降低。这些发现表明布氏杆菌在喜马拉雅旱獭中引发了免疫反应。
本研究初步探讨了布氏杆菌感染旱獭血液生化指标的变化。应进一步探讨喜马拉雅旱獭中布氏杆菌感染与血液生化指标之间的相互作用。
