Brucher J M, De Smet Y D, Gonsette R E
J Neurol. 1986 Oct;233(5):267-70. doi: 10.1007/BF00314157.
Previously undescribed morphological changes are reported in two cases of recent, non-septic cerebral embolism. These consisted of an arterial rupture involving the whole thickness of the wall. A direct tear by a sharp embolus seems unlikely but, as proposed by Villaret et al. in 1937, the arterial spasm may have occurred at the time of cerebral embolism. The embolic occlusion would prevent narrowing of the vascular lumen, so that focal spasm would rupture the arterial wall even at the level of a healthy and relatively thick media.
据报道，在两例近期发生的非感染性脑栓塞病例中出现了以前未描述过的形态学变化。这些变化包括动脉壁全层破裂。尖锐栓子直接撕裂的可能性似乎不大，但正如维拉雷等人在1937年所提出的，脑栓塞发生时可能出现了动脉痉挛。栓塞性阻塞会阻止血管腔变窄，因此即使在健康且相对较厚的中膜水平，局灶性痉挛也会使动脉壁破裂。
