轻链淀粉样变性导致结肠假性梗阻的罕见病因。

Deng Yunpeng Jack, Othman Bushra

Colorectal Surgical Department, Eastern Health, Box Hill, Victoria 3128, Australia.

Department of Medicine Nursing and Health Sciences, Monash University, Box Hill, Victoria 3128, Australia.

J Surg Case Rep. 2023 Sep 16;2023(9):rjad517. doi: 10.1093/jscr/rjad517. eCollection 2023 Sep.

In this case report, we discuss the rare presentation of a 56-year-old-gentleman with a history of light chain amyloidosis (AL), causing colonic pseudo-obstruction and requiring open subtotal colectomy and end ileostomy. This should remain a differential diagnosis in patients with known light chain AL presenting with nonspecific gastrointestinal symptoms such as constipation and abdominal pain. This prompts early investigation, such as endoscopy and tissue biopsy, and surgical intervention may be warranted.

在本病例报告中，我们讨论了一名56岁男性的罕见病例，他有轻链淀粉样变性（AL）病史，导致结肠假性梗阻，需要进行开放性次全结肠切除术和末端回肠造口术。对于已知患有轻链AL且出现便秘和腹痛等非特异性胃肠道症状的患者，这应始终作为鉴别诊断。这促使进行早期检查，如内窥镜检查和组织活检，可能需要进行手术干预。