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胆总管十二指肠壶腹异位开口:单中心经验。

Ectopic Opening of Common Bile Duct to Duodenal Bulb: A Single Tertiary Center Experience.

机构信息

Department of Gastroenterology, University of Health Sciences, Ankara City Hospital, Ankara, Turkey.

出版信息

Surg Laparosc Endosc Percutan Tech. 2023 Dec 1;33(6):640-644. doi: 10.1097/SLE.0000000000001219.

DOI:10.1097/SLE.0000000000001219
PMID:37725829
Abstract

BACKGROUND

The ectopic opening of the common bile duct(CBD) into the duodenal bulb is a rare biliary anomaly. The study aimed to reveal the experience with clinical and endoscopic outcomes in these patients.

MATERIALS AND METHODS

This study was conducted on 57 consecutive patients who underwent endoscopic retrograde cholangiopancreatography (ERCP) for ectopic opening of the CBD into the duodenal bulb at our institution between 2010 and 2020.

RESULTS

The median age was 59 years (49 males). A total of 146 ERCP procedures were performed (once in 26 patients and 2 or more times in 31 patients). Ten patients had a history of unsuccessful ERCP in an external center. The median follow-up time was 14.6 months. All patients had a slit-like opening of the CBD into the duodenal bulb, apical stenosis, and hook-shaped distal CBD. ERCP findings were CBD stone or dilatation in 55 patients and post-cholecystectomy biliary leakage in 2 patients. Balloon dilatation was performed for apical stenosis in 7 patients and distal CBD stenosis in 26 patients. During the first ERCP session, biliary stent/nasobiliary drainage was placed in 37 patients, and CBD stones were extracted in 19 patients without stenting. Biliodigestive anastomosis was applied to 13 patients, 5 of whom had recurrent cholangitis, 7 required recurrent ERCP, and one was due to the technical difficulty of ERCP.

CONCLUSIONS

Ectopic biliary opening should be remembered if the papilla cannot be seen in its usual place in a patient with apical stenosis. ERCP should be performed in experienced hands, and surgery should be considered in the need for recurrent ERCP.

摘要

背景

胆总管(CBD)异常开口于十二指肠球部是一种罕见的胆系异常。本研究旨在揭示此类患者的临床和内镜治疗结果。

材料与方法

本研究纳入了 2010 年至 2020 年期间,在我院因 CBD 异常开口于十二指肠球部而行内镜逆行胰胆管造影(ERCP)的 57 例连续患者。

结果

患者中位年龄为 59 岁(49 例男性)。共进行了 146 次 ERCP 检查(26 例患者仅行 1 次,31 例患者行 2 次或以上)。10 例患者在外院行 ERCP 治疗失败。中位随访时间为 14.6 个月。所有患者均存在 CBD 呈裂隙样开口于十二指肠球部、顶端狭窄和钩状远端 CBD。55 例患者存在 CBD 结石或扩张,2 例患者存在胆囊切除术后胆漏。7 例患者行顶端狭窄球囊扩张,26 例患者行远端 CBD 狭窄球囊扩张。初次 ERCP 时,37 例患者放置了胆道支架/鼻胆管引流,19 例未放置支架的患者行 CBD 结石取出术。13 例患者行胆肠吻合术,其中 5 例患者因反复胆管炎再次行 ERCP,7 例患者因需要再次行 ERCP,1 例患者因 ERCP 技术难度大而行手术治疗。

结论

若在顶端狭窄的患者中不能看到通常位置的乳头,应考虑存在异常胆管开口。应在有经验的医生手中进行 ERCP,对于需要反复行 ERCP 的患者应考虑手术治疗。

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