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功能性抗阻训练对非酒精性脂肪肝患者心脏和肝脏结构与功能的影响。

Effect of functional resistance training on the structure and function of the heart and liver in patients with non-alcoholic fatty liver.

机构信息

Department of Exercise Physiology, Faculty of Physical Education and Sport Sciences, University of Guilan, Rasht, Iran.

Medical Biotechnology Research Center, School of Paramedicine, Guilan University of Medical Sciences, Rasht, Iran.

出版信息

Sci Rep. 2023 Sep 19;13(1):15475. doi: 10.1038/s41598-023-42687-w.

Abstract

The current study is of the quasi-experimental type, with a pre-and post-test design, and subjects were randomly assigned to one of two groups: control (n = 8) and experimental (test) (n = 8). Based on the patient's self-report and using daily diet control tables, the patient's diet planning percentage of energy supply was managed and controlled for 3 days. The protocol for functional resistance training for these circular exercises, including the squat, lunge, bear crawl, rock press, jumping jack, and back fly lunge, was performed three times per week without specialized apparatus. Ejection fraction (EF) and fractional shortening (FS) were measured before and after functional resistance training, using echocardiography. Liver Stiffness and steatosis were measured using FibroScan, and the liver function was determined using biochemical assays. The average age of patients in the control group and the test group were 46.02 ± 5.4 and 48.6 ± 2.51, respectively. Pre-test and post-test of the body mass index were 32.06 ± 5.06 and 30.02 ± 3.97, and for the body fat percentage were 33.65 ± 6.09 and 25.41 ± 4.99. In non-alcoholic fatty liver patients, due to functional resistance training, EF (p-value = 0.003) and FS (p-value = 0.03) significantly increased, and C-reactive protein (Hs-CRP) (p-value = 0.001), steatosis (p-value = 0.04), and stiffness (p-value = 0.01) decreased. According to the results and without considering clinical trials, functional resistance training affects the structure and function of the heart and Liver in NAFLD patients.

摘要

本研究为准实验型,采用前后测设计,将受试者随机分为两组:对照组(n=8)和实验组(测试组)(n=8)。根据患者的自我报告,并使用日常饮食控制表,对患者的饮食计划能量供应比例进行管理和控制,为期 3 天。这些循环运动的功能性抗阻训练方案,包括深蹲、弓步蹲、熊爬、俯撑、开合跳和俯背飞步弓步蹲,无需专门器械,每周进行三次。使用超声心动图测量功能性抗阻训练前后的射血分数(EF)和缩短分数(FS)。使用 FibroScan 测量肝硬度和脂肪变性,使用生化检测确定肝功能。对照组和实验组患者的平均年龄分别为 46.02±5.4 和 48.6±2.51。身体质量指数的预测试和后测试分别为 32.06±5.06 和 30.02±3.97,体脂肪百分比分别为 33.65±6.09 和 25.41±4.99。在非酒精性脂肪性肝病患者中,由于功能性抗阻训练,EF(p 值=0.003)和 FS(p 值=0.03)显著增加,C 反应蛋白(Hs-CRP)(p 值=0.001)、脂肪变性(p 值=0.04)和硬度(p 值=0.01)降低。根据结果,不考虑临床试验,功能性抗阻训练会影响非酒精性脂肪性肝病患者的心脏和肝脏的结构和功能。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fc2d/10509216/ff0a8c29d8bf/41598_2023_42687_Fig1_HTML.jpg

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