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暴露于多种 PM 成分对中年及以上成年人超重和肥胖的综合影响:来自中国 125 个城市的全国性队列研究。

The combined effects of exposure to multiple PM components on overweight and obesity in middle-aged and older adults: a nationwide cohort study from 125 cities in China.

机构信息

Department of Epidemiology and Biostatistics, School of Public Health, Anhui Medical University, 81 Meishan Road, Shushan District, Hefei, 230032, Anhui, China.

出版信息

Environ Geochem Health. 2023 Nov;45(11):8749-8760. doi: 10.1007/s10653-023-01741-2. Epub 2023 Sep 19.

DOI:10.1007/s10653-023-01741-2
PMID:37726540
Abstract

The prevalence of overweight or obesity increased rapidly over the past decades in most countries, including China. However, little evidence exists about the effects of long-term exposure to PM components on overweight or obesity, particularly in developing countries. We measured different weight stages according to body mass index (BMI), and investigated the effects of exposure to PM components (ammonium [[Formula: see text]], sulfate [[Formula: see text]], nitrate [[Formula: see text]], black carbon and organic matter) on different BMI levels in middle-aged and elderly people of China. Our study explored the effects of single and multiple air pollution exposures on overweight and obesity by using the Generalized Linear Model and Quantile g-Computation model (QgC). This study found a significantly positive association between five PM components and overweight/obesity. In the QgC model, there was still a positive association between multiple exposure to PM components and overweight when all PM components were considered as a whole. In addition, males, the elderly, and urban residents were also more sensitive to five PM components.

摘要

在过去几十年中,大多数国家包括中国在内,超重或肥胖的患病率迅速上升。然而,关于长期暴露于 PM 成分对超重或肥胖的影响的证据很少,特别是在发展中国家。我们根据体重指数(BMI)测量了不同的体重阶段,并研究了暴露于 PM 成分([[Formula: see text]铵、[[Formula: see text]硫酸盐、[[Formula: see text]硝酸盐、黑碳和有机物)对中国中老年人不同 BMI 水平的影响。我们的研究通过广义线性模型和分位数 g-计算模型(QgC)探讨了单一和多种空气污染暴露对超重和肥胖的影响。这项研究发现,五种 PM 成分与超重/肥胖之间存在显著的正相关关系。在 QgC 模型中,当所有 PM 成分整体考虑时,PM 成分的多重暴露与超重之间仍然存在正相关关系。此外,男性、老年人和城市居民对五种 PM 成分也更为敏感。

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