Seo Hae Sun, Lee Sun Haeng, Yim Mi Hong, Jeong Yoon Kyoung, Chang Gyu Tae, Ahn Ye-Ji, Lee Jae Dong, Chung Won Seok, Ahn Se Young, Ahn Young Min, Lee Byung Cheol, Noh Ji-Won, Lee Boram
Department of Korean Pediatrics, College of Korean Medicine, Kyung Hee University, Kyung Hee University Medical Center, Seoul, South Korea.
Digital Health Research Division, Korea Institute of Oriental Medicine, Daejeon, South Korea.
Diabetes Metab Syndr Obes. 2023 Sep 15;16:2821-2832. doi: 10.2147/DMSO.S426848. eCollection 2023.
Integrative Korean medicine treatment (IKM), including herbal medicine (HM) and acupuncture, has been widely used for obesity and overweight in children and adolescents in South Korea. We investigated the real-world usage status and the potential effect of the IKM for obesity and overweight in children and adolescents.
Multicenter medical charts were retrospectively reviewed of obese and overweight children and adolescents who visited Korean medicine institutions with the goal of weight control for the first time and received IKM, to analyze the usage status and effect of IKM. We defined IKM responders as those with an improved obesity grade on the body mass index (BMI) percentile and analyzed their characteristics.
Medical charts of 209 patients (183 obese and 26 overweight) with a mean age of 11.45 years were examined. Patients visited the institution a mean of 5.95 times, and HM alone and HM plus acupuncture were frequently used IKM. HM was prescribed to 205 patients, 167 of whom received an HM prescription containing Ephedrae Herba. An HM of the decoction type was prescribed to 189 patients, and the average treatment duration was 76.54 days. After IKM, the percentile and z-score of BMI and weight significantly declined and height percentile and z-score were significantly enhanced, without serious adverse events. In the IKM responders, age, and the proportion of girls and overweight were significantly higher, and the percentile and z-score of height, weight, and BMI were significantly lower.
This is the first study to examine the real-world usage of IKM for obesity and overweight in children and adolescents. A significant improvement in obesity-related outcome measures after IKM, illustrated the potential effect of IKM.
综合韩医治疗(IKM),包括草药医学(HM)和针灸,在韩国已被广泛用于治疗儿童和青少年肥胖及超重问题。我们调查了IKM在儿童和青少年肥胖及超重治疗中的实际使用情况及其潜在效果。
对首次前往韩医机构以控制体重为目的并接受IKM治疗的肥胖和超重儿童及青少年的多中心病历进行回顾性分析,以分析IKM的使用情况和效果。我们将IKM治疗有反应者定义为那些体重指数(BMI)百分位数肥胖等级得到改善的患者,并分析了他们的特征。
共检查了209例患者(183例肥胖患者和26例超重患者)的病历,平均年龄为11.45岁。患者平均就诊5.95次,单独使用HM以及HM加针灸是常用的IKM治疗方式。205例患者接受了HM治疗,其中167例接受了含有麻黄的HM处方。189例患者接受了汤剂类型的HM治疗,平均治疗时长为76.54天。IKM治疗后,BMI和体重的百分位数及z分数显著下降,身高百分位数和z分数显著提高,且无严重不良事件发生。在IKM治疗有反应者中,年龄、女孩比例和超重比例显著更高,而身高、体重和BMI的百分位数及z分数显著更低。
这是第一项研究IKM在儿童和青少年肥胖及超重治疗中实际使用情况的研究。IKM治疗后肥胖相关指标显著改善,说明了IKM的潜在效果。