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北欧大学医院鼻窦肿瘤的内镜治疗:一项调查

Endoscopic management of sinonasal tumours in the Nordic university hospitals: a survey.

作者信息

Korsström Carl, Lilja Markus, Hammarstedt-Nordenvall Lalle, Mäkitie Antti, Haapaniemi Aaro

机构信息

Department of Otorhinolaryngology-Head and Neck Surgery, University of Helsinki and HUS Helsinki University Hospital, P.O. Box 263, 00029 HUS, Helsinki, Finland.

Division of Ear, Nose and Throat Diseases, Department of Clinical Sciences, Intervention and Technology, Karolinska Institutet and Karolinska University Hospital, Stockholm, Sweden.

出版信息

Eur Arch Otorhinolaryngol. 2024 Feb;281(2):785-794. doi: 10.1007/s00405-023-08229-w. Epub 2023 Sep 21.

Abstract

PURPOSE

The Nordic countries (27 M) all have comparable, publicly funded healthcare systems, and the management of sinonasal tumours is centralised to the 21 university hospitals. We sought to assess and compare the treatment practice of sinonasal tumours across the Nordic countries.

METHODS

A web-based questionnaire was sent to all university hospital departments of otorhinolaryngology-head and neck surgery in the Nordic countries.

RESULTS

Answers were obtained from all 21 Nordic university hospitals. The endoscopic approach was widely utilised by all, with most (62%) centres reporting 3-4 surgeons performing endoscopic sinonasal tumour surgery. Finland reported the lowest rates of centralisation among university hospitals despite having the highest number of 0.1-1 M catchment population hospitals. Most centres (88%) opted for the endoscopic approach in a patient case warranting medial maxillectomy. In a case of a Kadish C esthesioneuroblastoma, most (52%) of the centres preferred an endoscopic approach. Most centres (62%) reported favouring the endoscopic approach in a case describing a juvenile angiofibroma. Regarding a case describing a sinonasal undifferentiated carcinoma, consensus was tied (38% vs. 38%) between endoscopic resection followed by postoperative (chemo)radiotherapy (RT/CRT) and induction chemotherapy followed by RT/CRT or surgery followed by RT/CRT.

CONCLUSION

Endoscopic approach was widely utilised in the Nordic countries. The case-based replies showed differences in treatment practice, both internationally and nationally. The rate of centralisation among university hospitals remains relatively low, despite the rarity of these tumours.

摘要

目的

北欧国家(共2700万人)均拥有类似的公共资助医疗体系,鼻窦肿瘤的治疗集中于21家大学医院。我们试图评估和比较北欧国家鼻窦肿瘤的治疗实践。

方法

向北欧国家所有大学医院的耳鼻咽喉头颈外科发送了一份基于网络的调查问卷。

结果

收到了所有21家北欧大学医院的回复。所有医院都广泛采用了内镜手术方法,大多数(62%)中心报告称有3至4名外科医生进行鼻窦肿瘤内镜手术。芬兰报告称,尽管其拥有0.1至100万人口服务医院的数量最多,但其大学医院的集中化率却是最低的。在需要进行上颌骨内侧切除术的患者病例中,大多数中心(88%)选择了内镜手术方法。在卡迪什C期嗅神经母细胞瘤病例中,大多数中心(52%)更倾向于采用内镜手术方法。在描述青少年血管纤维瘤的病例中,大多数中心(62%)报告称倾向于采用内镜手术方法。对于描述鼻窦未分化癌的病例,在内镜切除术后进行术后(化疗)放疗(RT/CRT)与诱导化疗后进行RT/CRT或手术加RT/CRT之间达成了平手(38%对38%)。

结论

内镜手术方法在北欧国家被广泛应用。基于病例的回复显示,在国际和国内的治疗实践中均存在差异。尽管这些肿瘤较为罕见,但大学医院的集中化率仍然相对较低。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a6aa/10796644/18cc34239ba5/405_2023_8229_Fig1_HTML.jpg

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