Wileman Justin M, Price Marianne O, Price Francis W
Price Vision Group, Indianapolis, IN; and.
Cornea Research Foundation of America, Indianapolis, IN.
Cornea. 2024 Feb 1;43(2):257-260. doi: 10.1097/ICO.0000000000003397. Epub 2023 Sep 21.
The purpose of this study was to document, to our knowledge, the first reported case of keratoconus progression accompanied with newly diagnosed pellucid marginal degeneration after corneal cross-linking (CXL).
A novel case of further keratoconus progression plus development of pellucid marginal degeneration in the same eye after CXL was documented with supporting evidence from Scheimpflug and optical coherence tomography imaging.
A male patient was diagnosed with progressive keratoconus in the left eye and treated with CXL when aged 25 years. Although strongly cautioned not to rub his eyes, he admitted that he continued eye rubbing in association with atopic disease. At a follow-up examination 3.5 years after CXL, progressive keratoconus was detected and pellucid marginal degeneration was newly diagnosed in the left eye. The eye was retreated with CXL.
This case illustrates that progressive keratoconus and pellucid marginal degeneration can occur in the same eye after CXL and demonstrates the deleterious effects that can develop with continued eye rubbing.
据我们所知，本研究旨在记录首例经报道的圆锥角膜进展并伴有角膜交联（CXL）后新诊断的透明边缘变性的病例。
记录了1例CXL后同一眼圆锥角膜进一步进展并伴有透明边缘变性的新病例，并提供了来自Scheimpflug和光学相干断层扫描成像的支持证据。
一名男性患者在25岁时被诊断为左眼进行性圆锥角膜，并接受了CXL治疗。尽管被强烈告诫不要揉眼，但他承认因特应性疾病仍继续揉眼。在CXL后3.5年的一次随访检查中，检测到左眼圆锥角膜进展，并新诊断出透明边缘变性。该眼再次接受了CXL治疗。
本病例表明，CXL后同一眼可发生进行性圆锥角膜和透明边缘变性，并证明了持续揉眼可能产生的有害影响。
