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采用聚四氟乙烯或聚酯基内置移植物进行择期血管内动脉瘤修复术后 II 型内漏的发生率。

Prevalence of type II endoleak after elective endovascular aneurysm repair with polytetrafluoroethylene- or polyester-based endografts.

机构信息

Department of Surgery, Rijnstate, Arnhem, the Netherlands.

Department of Vascular Surgery, Amsterdam UMC, Amsterdam, the Netherlands.

出版信息

J Vasc Surg. 2024 Jan;79(1):24-33. doi: 10.1016/j.jvs.2023.09.019. Epub 2023 Sep 19.

Abstract

OBJECTIVE

Type II endoleak is the most frequent complication after endovascular abdominal aneurysm repair. Polytetrafluoroethylene and polyester (PE) are the two most commonly used graft materials in endovascular aneurysm repair (EVAR) devices. Biological properties of the material might influence the appearance and persistence of type II endoleak (T2EL). Therefore, the aim of this study was to evaluate potential differences in the prevalence of T2EL after EVAR between polytetrafluoroethylene (PTFE) and PE endografts in patients electively treated for an infrarenal abdominal aortic aneurysm.

METHODS

A single-center, retrospective, observational study was conducted between January 2011 and January 2022. Preoperative, procedural, and follow-up data were derived from electronic health records. Imaging included computed tomography scans, and/or duplex ultrasound examination. The primary end point was the prevalence of T2EL diagnosed within 1 year after EVAR. Secondary end points included the prevalence of T2EL throughout follow-up, early (≤30 days) and late (>30 days) T2EL, the rate of T2EL disappearance during the follow-up period, the prevalence of type I and III endoleak, and T2EL-related reinterventions.

RESULTS

Follow-up was available for 394 patients, 245 in the PE and 149 in the PTFE group. The prevalence of T2EL diagnosed within 1 year after endovascular repair was 11.8% in the PE group and 21.5% in the PTFE group (P = .010). There was no significant difference in early (≤30 days) and late (>30 days) T2EL between groups (P = .270 and P = .311). There was no difference in the freedom from endoleak type II reinterventions between groups (P = .877).

CONCLUSIONS

The prevalence of T2EL after elective EVAR is significantly higher with the use of PTFE-based endografts compared with PE-based endografts. This difference is mostly based on T2EL diagnosed after 30 days of follow-up.

摘要

目的

II 型内漏是血管内腹主动脉瘤修复后最常见的并发症。聚四氟乙烯(PTFE)和聚酯(PE)是血管内动脉瘤修复(EVAR)装置中最常用的两种移植物材料。材料的生物学特性可能会影响 II 型内漏(T2EL)的出现和持续时间。因此,本研究旨在评估在择期治疗肾下腹主动脉瘤的患者中,使用 PTFE 和 PE 血管内移植物进行 EVAR 后 T2EL 的发生率是否存在差异。

方法

这是一项于 2011 年 1 月至 2022 年 1 月期间进行的单中心、回顾性、观察性研究。术前、手术中和随访数据来自电子健康记录。影像学检查包括计算机断层扫描和/或双功能超声检查。主要终点是在 EVAR 后 1 年内诊断出的 T2EL 发生率。次要终点包括整个随访期间 T2EL 的发生率、早期(≤30 天)和晚期(>30 天)T2EL、随访期间 T2EL 消失的发生率、I 型和 III 型内漏的发生率以及与 T2EL 相关的再介入治疗。

结果

394 例患者可获得随访结果,其中 PE 组 245 例,PTFE 组 149 例。PE 组和 PTFE 组在血管内修复后 1 年内诊断出的 T2EL 发生率分别为 11.8%和 21.5%(P=0.010)。两组间早期(≤30 天)和晚期(>30 天)T2EL 发生率无显著差异(P=0.270 和 P=0.311)。两组间 T2EL 型 II 再介入治疗的无失败率无差异(P=0.877)。

结论

与使用 PE 基移植物相比,使用 PTFE 基移植物进行择期 EVAR 后 T2EL 的发生率显著更高。这种差异主要基于 30 天随访后诊断出的 T2EL。

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