Levine B, Caplan Y H, Kauffman G
J Anal Toxicol. 1986 Sep-Oct;10(5):209-10. doi: 10.1093/jat/10.5.209.
A case involving an accidental overdose fatality resulting from an intravenous injection of crushed Ritalin (methylphenidate) tablets is presented. The drug was quantified by gas chromatography/nitrogen-phosphorus detection and confirmed by gas chromatography/mass spectrometry. Concentrations of drug were as follows: blood, 2.8 mg/L; bile, 5.7 mg/L; kidney, 3.0 mg/kg; liver, 2.1 mg/kg; and stomach contents, 1.6 mg total. Other drugs and volatile substances were not detected.
本文介绍了一例因静脉注射碾碎的利他林(哌醋甲酯)片剂导致意外过量致死的案例。通过气相色谱/氮磷检测对药物进行定量,并通过气相色谱/质谱法进行确认。药物浓度如下:血液,2.8毫克/升;胆汁,5.7毫克/升;肾脏,3.0毫克/千克;肝脏,2.1毫克/千克;胃内容物,总量1.6毫克。未检测到其他药物和挥发性物质。