Lavee J, Porat L, Smolinsky A, Hegesh J, Neufeld H N, Goor D A
J Thorac Cardiovasc Surg. 1986 Nov;92(5):944-9.
The results of membranectomy and deep myectomy in the left ventricular outflow tract were compared to those of membranectomy and myotomy in 42 patients who underwent surgical repair of discrete and tunnel subaortic stenosis. Fifteen consecutive patients (Group A) underwent membranectomy and myotomy, and 27 consecutive patients (Group B) underwent membranectomy and myectomy. Two patients of Group A and nine of Group B had tunnel subaortic stenosis. The preoperative mean (+/- standard deviation) peak systolic gradients across the left ventricular outflow tract in patients with discrete subaortic stenosis types I and II were 64 +/- 29 mm Hg in Group A and 52 +/- 3 mm Hg in Group B (p = not significant). In the patients with tunnel subaortic stenosis the preoperative mean gradients were 97 +/- 74 mm Hg in Group A and 73 +/- 26 mm Hg in Group B (p = not significant). In patients with discrete subaortic stenosis types I and II, postoperative catheterization at a mean follow-up of 21 months revealed residual mean gradients of 29 +/- 24 mm Hg in Group A and 10 +/- 13 mm Hg in Group B (p less than 0.01). In the patients with tunnel subaortic stenosis, the postoperative mean gradients were 25 +/- 7 and 30 +/- 30 mm Hg in Groups A and B, respectively (p = not significant). We conclude that in the surgical management of discrete subaortic stenosis types I and II, deep myectomy (in addition to membranectomy) produces better relief of the left ventricular outflow obstruction than do membranectomy and myotomy. In patients with tunnel subaortic stenosis myectomy is less effective than in the non-tunnel type but still produces acceptable results and may delay radical procedures to a later age.
对42例接受孤立性和隧道型主动脉瓣下狭窄手术修复的患者,比较了左心室流出道膜切除术和深部心肌切除术与膜切除术和肌切开术的效果。连续15例患者(A组)接受膜切除术和肌切开术,连续27例患者(B组)接受膜切除术和心肌切除术。A组2例患者和B组9例患者患有隧道型主动脉瓣下狭窄。I型和II型孤立性主动脉瓣下狭窄患者术前左心室流出道平均(±标准差)收缩期峰值压差,A组为64±29 mmHg,B组为52±3 mmHg(p值无统计学意义)。隧道型主动脉瓣下狭窄患者术前平均压差,A组为97±74 mmHg,B组为73±26 mmHg(p值无统计学意义)。I型和II型孤立性主动脉瓣下狭窄患者,平均随访21个月后的术后心导管检查显示,A组残余平均压差为29±24 mmHg,B组为10±13 mmHg(p<0.01)。隧道型主动脉瓣下狭窄患者,A组和B组术后平均压差分别为25±7 mmHg和30±30 mmHg(p值无统计学意义)。我们得出结论,在I型和II型孤立性主动脉瓣下狭窄的外科治疗中,深部心肌切除术(除膜切除术外)比膜切除术和肌切开术能更好地缓解左心室流出道梗阻。在隧道型主动脉瓣下狭窄患者中,心肌切除术的效果不如非隧道型,但仍能产生可接受的结果,并且可能将根治性手术推迟到较晚年龄。