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先前健康儿童的坏疽性脓皮病皮肤病变。

Ecthyma gangrenosum skin lesions in previously healthy children.

作者信息

Cohen Neta, Capua Tali, Bilavsky Efraim, Dias-Polak Hila, Levin Dror, Grisaru-Soen Galia

机构信息

Department of Pediatrics, Dana-Dwek Children's Hospital, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel; Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.

出版信息

Acta Paediatr. 2015 Mar;104(3):e134-8. doi: 10.1111/apa.12889. Epub 2015 Jan 30.

DOI:10.1111/apa.12889
PMID:25469722
Abstract

UNLABELLED

Ecthyma gangrenosum (EG) is an uncommon skin lesion that usually develops in patients with known immune deficiency or who are on immunosuppressive treatment. We report on five previously healthy children presenting with EG. Three of them developed severe neutropaenia. Immunologic work-up revealed chronic neutropaenia in two.

CONCLUSION

Recognition of EG is essential for providing early appropriate empiric antibiotic treatment. An immunologic work-up should be done, although a concomitant viral infection can be the predisposing factor.

摘要

未标注

坏疽性脓皮病（EG）是一种罕见的皮肤病变，通常发生在已知免疫缺陷或正在接受免疫抑制治疗的患者中。我们报告了5例以前健康的儿童出现EG的病例。其中3例出现严重中性粒细胞减少。免疫检查发现2例为慢性中性粒细胞减少。

结论

认识EG对于早期给予适当的经验性抗生素治疗至关重要。尽管合并病毒感染可能是诱发因素，但仍应进行免疫检查。

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