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白塞综合征复发性局灶性肌筋膜炎酷似感染性肌筋膜炎：一例报告

Recurrent focal myofasciitis of Behçet syndrome mimics infectious myofasciitis: a case report.

作者信息

Chung Sang Wan, Lee Joo Ho, Ha You-Jung, Kang Eun Ha, Lee Yun Jong

机构信息

Division of Rheumatology, Department of Internal Medicine, Kyung Hee University Hospital, Kyung Hee University College of Medicine, Seoul, Korea.

Division of Rheumatology, Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, Korea.

出版信息

J Rheum Dis. 2023 Oct 1;30(4):268-271. doi: 10.4078/jrd.2023.0020. Epub 2023 Aug 30.

DOI:10.4078/jrd.2023.0020
PMID:37736593
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10509642/
Abstract

Behçet syndrome (BS) is a chronic inflammatory disease with multiorgan manifestations. However, muscular involvement in BS has rarely been reported. Herein, we report the case of a 30-year-old male with BS who had recurring pain and swelling of the lower legs. The patient was administered antibiotics on several occasions as the condition was misinterpreted to be infectious myositis. Magnetic resonance imaging revealed myofascial involvement with focal necrotic lesions, and muscle biopsy revealed acute suppurative myositis with perivascular infiltration of polymorphonuclear leukocytes. His symptoms improved after treatment with corticosteroids. Azathioprine and colchicine therapy was beneficial for preventing further relapse after short-term corticosteroid treatment. Therefore, BS should be considered in the differential diagnosis of focal suppurative myofasciitis.

摘要

白塞病（BS）是一种具有多器官表现的慢性炎症性疾病。然而，白塞病累及肌肉的情况鲜有报道。在此，我们报告一例30岁患有白塞病的男性患者，其小腿反复出现疼痛和肿胀。由于病情被误诊为感染性肌炎，该患者曾多次接受抗生素治疗。磁共振成像显示肌筋膜受累并伴有局灶性坏死病变，肌肉活检显示为急性化脓性肌炎，伴有多形核白细胞血管周围浸润。使用皮质类固醇治疗后，他的症状有所改善。硫唑嘌呤和秋水仙碱治疗有助于在短期皮质类固醇治疗后预防进一步复发。因此，在局灶性化脓性肌筋膜炎的鉴别诊断中应考虑白塞病。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9c7e/10509642/bfe4fb1235f3/jrd-30-4-268-f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9c7e/10509642/0784de43a68d/jrd-30-4-268-f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9c7e/10509642/bfe4fb1235f3/jrd-30-4-268-f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9c7e/10509642/0784de43a68d/jrd-30-4-268-f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9c7e/10509642/bfe4fb1235f3/jrd-30-4-268-f2.jpg

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本文引用的文献

1
Mucocutaneous Manifestations of Behçet's Disease.白塞病的皮肤黏膜表现
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Focal vasculitic myositis as a primary manifestation of Behçet's disease: a case series of 10 Korean patients in a locomotive medicine clinic.以局灶性血管炎性肌炎为主要表现的白塞病：机车医学诊所10例韩国患者的病例系列
Rheumatology (Oxford). 2021 Oct 2;60(10):4609-4615. doi: 10.1093/rheumatology/keab053.
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英夫利昔单抗治疗白塞病相关横纹肌溶解症
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Muscular involvement of Behçet's disease: ultrasonography, computed tomography, and magnetic resonance imaging findings.贝赫切特病的肌肉受累：超声、计算机断层扫描和磁共振成像的表现。
Clin Imaging. 2012 Sep-Oct;36(5):643-6. doi: 10.1016/j.clinimag.2011.11.008. Epub 2012 Jun 8.
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New insights in the clinical understanding of Behçet's disease.对贝赫切特病临床认识的新见解。
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