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癌症患者自杀的地区差异:日本全国基于人群的研究。

Regional disparities in suicide among patients with cancer: A nationwide population-based study in Japan.

机构信息

Division of Survivorship Research, National Cancer Center Institute for Cancer Control, Tokyo, Japan.

Department of Stress Sciences and Psychosomatic Medicine, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.

出版信息

Cancer Med. 2023 Oct;12(19):20052-20058. doi: 10.1002/cam4.6574. Epub 2023 Sep 22.

Abstract

BACKGROUND

This study aimed to explore prefecture-level differences in suicide risk among patients with cancer in Japan.

METHODS

Data from the National Cancer Registry, which covers the entire Japanese population, were used. Patients diagnosed with cancer between 2016 and 2017 were included. The standardized mortality ratio (SMR) for suicide within 2 years after cancer diagnosis was quantified compared with the general population for each prefecture. Multivariate Poisson regression analysis was conducted to quantify the adjusted relative risk using Hokkaido as the reference.

RESULTS

The analysis included 2,133,502 patients. The SMRs were high among patients with cancer residing in certain prefectures, such as the Hokuriku region (the middle and western parts of Japan's main island). These areas also exhibited a significant relative risk in the Poisson regression model.

CONCLUSION

The results demonstrated that patients with cancer in certain prefectures in Japan have a high suicide risk.

摘要

背景

本研究旨在探讨日本癌症患者的自杀风险在县级层面上的差异。

方法

使用覆盖全日本人口的国立癌症登记处的数据,纳入了 2016 年至 2017 年间诊断为癌症的患者。对每个县癌症诊断后 2 年内自杀的标准化死亡率(SMR)与普通人群进行了量化比较。采用北海道作为参照,进行多变量泊松回归分析,以量化调整后的相对风险。

结果

分析共纳入 2133502 名患者。居住在某些县(如日本本州岛中部和西部的北陆地区)的癌症患者的 SMR 较高。在泊松回归模型中,这些地区也显示出显著的相对风险。

结论

研究结果表明,日本某些县的癌症患者自杀风险较高。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4bab/10587921/20625cb0b638/CAM4-12-20052-g001.jpg

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