Lymphoma Service, Division of Hematologic Malignancies, Memorial Sloan Kettering Cancer Center, New York, NY.
Department of Medicine, Baylor College of Medicine, Houston, TX.
Blood. 2023 Dec 28;142(26):2327-2331. doi: 10.1182/blood.2023021274.
In this real-world evaluation of tafasitamab-lenalidomide (TL) in relapsed or refractory LBCL, patients receiving TL had higher rates of comorbidities and high-risk disease characteristics, and substantially lower progression-free survival and overall survival, compared with the L-MIND registration clinical trial for TL.
在这项关于 tafasitamab-来那度胺(TL)治疗复发或难治性弥漫性大 B 细胞淋巴瘤(LBCL)的真实世界评估中,与 TL 的 L-MIND 注册临床试验相比,接受 TL 治疗的患者合并症和高危疾病特征发生率更高,无进展生存期和总生存期显著降低。