肺和肌肉中从头合成sn-甘油-3-磷酸胆碱合成酶的活性及其亚细胞定位。
De novo sn-glycerol-3-phosphorylcholine synthetase activity in lung and muscle and its subcellular location.
作者信息
Infante J P
出版信息
Mol Cell Biochem. 1986 Aug;71(2):135-7. doi: 10.1007/BF00214772.
PMID:3773885
Abstract
The activity of glycerophosphorylcholine synthetase, a newly discovered enzyme involved in the synthesis of acyl-specific phosphatidylcholines, is reported in rat lung and muscle. Its subcellular location appears to be mitochondrial. The implication of these findings in the synthesis of lung surfactant and the pathology of muscular dystrophy are discussed.
摘要
甘油磷酸胆碱合成酶是一种新发现的参与酰基特异性磷脂酰胆碱合成的酶，本文报道了该酶在大鼠肺和肌肉中的活性。其亚细胞定位似乎在线粒体。本文还讨论了这些发现对肺表面活性剂合成和肌肉萎缩症病理学的意义。
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