Devita Sella, Deforges Camille, Bickle-Graz Myriam, Tolsa Jean-François, Sandoz Vania, Horsch Antje
Institute of Higher Education and Research in Healthcare (IUFRS), University of Lausanne and Lausanne University Hospital, Lausanne, Switzerland.
Department Woman-Mother-Child, Clinic of Neonatology, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.
J Reprod Infant Psychol. 2025 Jun;43(3):718-732. doi: 10.1080/02646838.2023.2261057. Epub 2023 Sep 23.
Childbirth-related posttraumatic stress symptoms (CB-PTSS) including general symptoms (GS, i.e., mainly negative cognitions and mood and hyperarousal symptoms) and birth-related symptoms (BRS, i.e., mostly re-experiencing and avoidance symptoms) may disrupt mother-infant bonding and infant development. This study investigated prospective and cross-sectional associations between maternal CB-PTSS and mother-infant bonding or infant development (language, motor, and cognitive).
We analysed secondary data of the control group of a randomised control trial (NCT03576586) with full-term French-speaking mother-infant dyads ( = 55). Maternal CB-PTSS and mother-infant bonding were assessed via questionnaires at six weeks (T1) and six months (T2) postpartum: PTSD Checklist for DSM-5 (PCL-5) and Mother-Infant Bonding Scale (MIBS). Infant development was assessed with the Bayley Scales of Infant Development at T2. Sociodemographic and medical data were collected from questionnaires and medical records. Bivariate and multivariate regression were used.
Maternal total CB-PTSS score at T1 was associated with poorer bonding at T2 in the unadjusted model (B = 0.064, = 0.043). In the adjusted model, cross-sectional associations were found at T1 between a higher total CB-PTSS score and poorer bonding (B = 0.134, = 0.017) and between higher GS and poorer bonding (B = 0.306, = 0.002). Higher BRS at T1 was associated with better infant cognitive development at T2 in the unadjusted model (B = 0.748, = 0.026).
Results suggest that CB-PTSS were associated with mother-infant bonding difficulties, while CB-PTSS were not significantly associated with infant development. Additional studies are needed to increase our understanding of the intergenerational consequences of perinatal trauma.
分娩相关的创伤后应激症状（CB-PTSS）包括一般症状（GS，即主要为负面认知、情绪和过度警觉症状）和与分娩相关的症状（BRS，即大多为重新体验和回避症状），可能会破坏母婴联结和婴儿发育。本研究调查了母亲的CB-PTSS与母婴联结或婴儿发育（语言、运动和认知）之间的前瞻性和横断面关联。
我们分析了一项随机对照试验（NCT03576586）对照组的二次数据，该试验对象为说法语的足月母婴二元组（n = 55）。在产后六周（T1）和六个月（T2）通过问卷评估母亲的CB-PTSS和母婴联结：《精神疾病诊断与统计手册》第5版创伤后应激障碍检查表（PCL-5）和母婴联结量表（MIBS）。在T2时用贝利婴儿发育量表评估婴儿发育。通过问卷和病历收集社会人口学和医学数据。使用双变量和多变量回归分析。
在未调整模型中，T1时母亲的CB-PTSS总分与T2时较差的联结相关（B = 0.064，P = 0.043）。在调整模型中，在T1时发现较高的CB-PTSS总分与较差的联结之间存在横断面关联（B = 0.134，P = 0.017），较高的GS与较差的联结之间也存在横断面关联（B = 0.306，P = 0.002）。在未调整模型中，T1时较高的BRS与T2时较好的婴儿认知发育相关（B = 0.748，P = 0.026）。
结果表明，CB-PTSS与母婴联结困难相关，而CB-PTSS与婴儿发育无显著关联。需要进一步研究以增进我们对围产期创伤代际后果的理解。
