UKRAINIAN MILITARY MEDICAL ACADEMY, KYIV, UKRAINE.
Wiad Lek. 2023;76(8):1725-1729. doi: 10.36740/WLek202308103.
The aim: To substantiate, develop and apply in clinical practice a method for the treatment of combined acne and genitourinary infections caused by chlamydia and mycoplasmas.
Materials and methods: Acne was diagnosed clinically. Chlamydia trachomatis; Mycoplasma genitalium; Mycoplasma hominis; Ureaplasma urealyticum were identified using polymerase chain reaction. 30 patients with combined acne and urogenital chlamydia and/or mycoplasmas received sequential oral antibiotic therapy with josamycin (1500 mg daily) and gatifloxacin (400 mg daily) for 10 days each. Simultaneously with antibiotic therapy, concomitant symptomatic and topical treatment was provided.
Results: The elimination of pathogens of urogenital chlamydia and/or mycoplasmas was achieved with 29 out of 30 patients (93.3%). At the same time a complete regression of facial rash inflammatory elements was detected at 18 (60%) treated patients, while with the remaining 12 (40%) the regression was significant.
Conclusions: Antibiotic therapy was used in the treatment for both acne and urogenital chlamydia and/or mycoplasmas. An original method of complex treatment of combined acne and urogenital chlamydia and/or mycoplasmas was substantiated, developed and successfully applied. The offered method of treatment can be considered as a proof of high effectiveness both for elimination of pathogens from the genitourinary system of patients, and for complete or significant elimination of inflammatory facial rash.
证实、开发和应用一种治疗由衣原体和支原体引起的痤疮和泌尿生殖道感染的方法。
根据临床诊断痤疮。使用聚合酶链反应鉴定沙眼衣原体；生殖支原体；人型支原体；解脲支原体。30 例合并痤疮和泌尿生殖道衣原体和/或支原体感染的患者接受序贯口服抗生素治疗，分别使用交沙霉素（1500mg 每日）和加替沙星（400mg 每日）治疗 10 天。同时进行抗生素治疗，同时进行对症和局部治疗。
29 例（93.3%）患者消除了泌尿生殖道衣原体和/或支原体的病原体。同时，18 例（60%）治疗患者面部皮疹炎症要素完全消退，而 12 例（40%）患者则显著消退。
对于痤疮和泌尿生殖道衣原体和/或支原体感染，采用了抗生素治疗。证实、开发和成功应用了一种治疗合并痤疮和泌尿生殖道衣原体和/或支原体感染的综合治疗的新方法。所提供的治疗方法可以被认为是消除患者泌尿生殖道病原体的高效性的证明，以及消除炎症性面部皮疹的完全或显著消退。
