活体肾供体妊娠：基于证据的综述。
Pregnancy in Living Kidney Donors: An Evidence-Based Review.
作者信息
Artan Ayse Serra, Fleetwood Vidyaratna, Guller Nurane, Oto Ozgur Akin, Mirioglu Safak, Yazici Halil, Turkmen Aydin, Caliskan Yasar, Lentine Krista L
机构信息
Division of Nephrology, Department of Internal Medicine, Istanbul University Istanbul Faculty of Medicine, Istanbul, Turkey.
Center for Abdominal Transplantation, Saint Louis University School of Medicine, Saint Louis, MO, USA.
出版信息
Curr Transplant Rep. 2023 Sep;10(3):110-116. doi: 10.1007/s40472-023-00402-8. Epub 2023 Aug 17.
PURPOSE OF REVIEW
To review the current studies and guidelines on the risk of adverse pregnancy outcomes in female kidney donors.
RECENT FINDINGS
Living kidney donors include a significant amount of young women of child-bearing age. Safety and possible risks of pregnancy after donation are a concern for female kidney donor candidates. Many current studies indicate a higher risk of preeclampsia in women after kidney donation. Considering the increasing number of living kidney donors, the maternal outcomes of living kidney donation is an active area of research.
SUMMARY
Guidelines and consensus statements on the risk of pregnancy in living kidney donors recommend close monitoring of blood pressure, weight gain, and proteinuria during pregnancy. Current studies indicate an increased risk of hypertensive disorders of pregnancy in living kidney donors. Counseling and informing donor candidates about the possible risks is important.
综述目的
回顾目前关于女性肾捐赠者不良妊娠结局风险的研究及指南。
最新发现
活体肾捐赠者中有相当数量的育龄年轻女性。捐赠后妊娠的安全性及可能风险是女性肾捐赠候选者所关注的问题。目前许多研究表明，肾捐赠女性发生先兆子痫的风险更高。鉴于活体肾捐赠者数量不断增加，活体肾捐赠的孕产妇结局是一个活跃的研究领域。
总结
关于活体肾捐赠者妊娠风险的指南和共识声明建议在孕期密切监测血压、体重增加及蛋白尿情况。目前研究表明，活体肾捐赠者发生妊娠高血压疾病的风险增加。向捐赠候选者咨询并告知其可能风险很重要。
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