Mattig Isabel, Barbieri Fabian, Kasner Mario, Romero Dorta Elena, Heinrich-Schüler Anna Lisa, Zhu Miry, Stangl Karl, Landmesser Ulf, Reinthaler Markus, Dreger Henryk
Department of Cardiology, Angiology and Intensive Care Medicine, Deutsches Herzzentrum der Charité, Campus Charité Mitte, Berlin, Germany.
Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.
Front Cardiovasc Med. 2023 Sep 8;10:1232327. doi: 10.3389/fcvm.2023.1232327. eCollection 2023.
In recent years, new interventional therapies for tricuspid regurgitation (TR) demonstrated their effectiveness in reducing TR severity and improving symptoms. Currently, tricuspid transcatheter edge-to-edge repair (T-TEER) and percutaneous annuloplasty are the most widely used techniques in Europe. In this retrospective study, we compared procedural characteristics and learning curves of both TR devices in a real-world cohort.
Eligible patients with severe to torrential TR underwent either percutaneous annuloplasty or T-TEER as recommended by the local heart team. Patients with combined mitral and tricuspid interventions were excluded from the analysis. The study focused on procedural characteristics, TR reduction and learning curves.
A total of 122 patients underwent either percutaneous annuloplasty (= 64) or T-TEER (= 58) with a technical and device success rate of 98% and 97%, respectively. Reasons for technical failure included right coronary artery (RCA) dissection prior to percutaneous annuloplasty, and two single leaflet device attachments (SLDA) during T-TEER implantation. The mean improvement of TR severity was 2.4 ± 0.8 degrees after T-TEER and 2.5 ± 0.8 after percutaneous annuloplasty. T-TEER procedures were shorter in terms of both procedure time and radiation exposure, while percutaneous annuloplasty, although taking longer, showed a significant reduction in procedure time over the course of the analysed period.
In summary, both interventional therapies reduce TR severity by approximately two degrees when used in the appropriate anatomy. The learning curve for annuloplasty group showed a significant decrease of procedure times.
近年来,三尖瓣反流(TR)的新型介入治疗方法已证明其在降低TR严重程度和改善症状方面的有效性。目前,三尖瓣经导管缘对缘修复术(T-TEER)和经皮瓣环成形术是欧洲使用最广泛的技术。在这项回顾性研究中,我们比较了这两种TR治疗设备在真实世界队列中的手术特征和学习曲线。
符合条件的重度至极重度TR患者按照当地心脏团队的建议接受经皮瓣环成形术或T-TEER。二尖瓣和三尖瓣联合干预的患者被排除在分析之外。该研究重点关注手术特征、TR减轻情况和学习曲线。
共有122例患者接受了经皮瓣环成形术(=64例)或T-TEER(=58例),技术成功率和器械成功率分别为98%和97%。技术失败的原因包括经皮瓣环成形术前右冠状动脉(RCA)夹层,以及T-TEER植入过程中的两次单叶瓣装置附着(SLDA)。T-TEER术后TR严重程度的平均改善为2.4±0.8度,经皮瓣环成形术后为2.5±0.8度。T-TEER手术在手术时间和辐射暴露方面都较短,而经皮瓣环成形术虽然耗时较长,但在分析期内手术时间显著缩短。
总之,两种介入治疗方法在适用于相应解剖结构时,均可使TR严重程度降低约2度。瓣环成形术组的学习曲线显示手术时间显著缩短。