Salih Abdulwahid M, Qaradakhy Aras J, Hassan Shko H, Abdullah Ari M, Dhahir Hardi Mohammed, Karim Sanaa O, Sofi Hawar A, Abdalla Berun A, Ali Muhammad Hassan, Kakamad Fahmi H
Department of Scientific Affairs, Smart Health Tower, Sulaimani, Kurdistan 46000, Iraq.
College of Medicine, University of Sulaimani, Sulaimani, Kurdistan 46000, Iraq.
Med Int (Lond). 2023 Sep 5;3(5):49. doi: 10.3892/mi.2023.109. eCollection 2023 Sep-Oct.
Tuberculosis of the thyroid gland is rare, and tuberculous granulomatous inflammation of the parathyroid glands is even rarer. The present study reports a rare case of primary hyperparathyroidism caused by tuberculous granulomatous inflammation. A 58-year-old female patient presented with generalized body pain persisting for 1 year. She had a history of recurrent renal stones (>20 times) and an incidental finding of multinodular goiter involving the parathyroid on neck ultrasound. A blood analysis revealed elevated levels of serum calcium (11.26 mg/dl) and parathyroid hormone (154.7 pg/ml). The patient underwent the resection of the affected left thyroid lobe under general anesthesia. A histopathological examination revealed parathyroid adenoma with caseating granulomatous inflammation involving the adenoma with focal lymphocytic thyroiditis of the left thyroid gland. Although granulomatous parathyroid disease with parathyroid adenoma causing hypercalcemia is an extremely rare event, it can occur. The treatment of choice is surgical resection.
甲状腺结核很罕见，甲状旁腺的结核性肉芽肿性炎症则更为罕见。本研究报告了一例由结核性肉芽肿性炎症引起的原发性甲状旁腺功能亢进的罕见病例。一名58岁女性患者出现全身疼痛持续1年。她有复发性肾结石病史（>20次），颈部超声偶然发现累及甲状旁腺的多结节性甲状腺肿。血液分析显示血清钙（11.26mg/dl）和甲状旁腺激素（154.7pg/ml）水平升高。患者在全身麻醉下接受了患侧左甲状腺叶切除术。组织病理学检查显示甲状旁腺腺瘤伴有干酪样肉芽肿性炎症累及腺瘤，左甲状腺有局灶性淋巴细胞性甲状腺炎。虽然伴有甲状旁腺腺瘤的肉芽肿性甲状旁腺疾病导致高钙血症是极其罕见的事件，但它是可能发生的。首选的治疗方法是手术切除。
