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川崎病的冠状动脉病变:1100例心脏导管检查结果

Coronary arterial lesions of Kawasaki disease: cardiac catheterization findings of 1100 cases.

作者信息

Suzuki A, Kamiya T, Kuwahara N, Ono Y, Kohata T, Takahashi O, Kimura K, Takamiya M

出版信息

Pediatr Cardiol. 1986;7(1):3-9. doi: 10.1007/BF02315475.

Abstract

In our institute, 1100 patients with a history of Kawasaki disease have been catheterized for selective coronary arteriography. Their age at examination ranged from four months to 13 years. Coronary artery lesions (CAL) were found in 262 patients. As far as the type of the CAL was concerned, occlusion was noted in 20 (7.6%), segmental stenosis in 15 (5.7%), localized stenosis in 62 (23.7%), aneurysm in 93 (35.5%), and dilatation in 72 patients (27.5%). In terms of the total number of lesions, there were 23 occlusions, 19 segmental stenoses, 109 localized stenoses, 449 aneurysms and 307 dilatations. The 262 patients with CAL were analyzed according to the interval from the onset to the time of selective coronary arteriography. The incidence of both occlusion and segmental stenosis was lowest in the group who were catheterized shortly after the onset of disease, whereas the prevalence of aneurysm was highest in this group. But the prevalence of dilatation was highest in the group of patients who were catheterized late. A total of 12 patients had to undergo femoral arterial thrombectomy for arterial thrombosis following the catheterization, but no other major complication was experienced.

摘要

在我们研究所,1100例有川崎病病史的患者接受了选择性冠状动脉造影导管插入术。他们接受检查时的年龄从4个月到13岁不等。262例患者发现有冠状动脉病变(CAL)。就CAL的类型而言,20例(7.6%)出现闭塞,15例(5.7%)出现节段性狭窄,62例(23.7%)出现局限性狭窄,93例(35.5%)出现动脉瘤,72例(27.5%)出现扩张。就病变总数而言,有23处闭塞、19处节段性狭窄、109处局限性狭窄、449处动脉瘤和307处扩张。对262例有CAL的患者根据发病至选择性冠状动脉造影的时间间隔进行了分析。闭塞和节段性狭窄的发生率在疾病发作后不久接受导管插入术的组中最低,而动脉瘤的患病率在该组中最高。但扩张的患病率在晚期接受导管插入术的患者组中最高。共有12例患者在导管插入术后因动脉血栓形成而不得不接受股动脉血栓切除术,但未出现其他重大并发症。

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