Mubarak Muhammed, Raza Amber, Rashid Rahma, Shakeel Shaheera
Department of Histopathology, Sindh Institute of Urology and Transplantation, Karachi 74200, Sindh, Pakistan.
Department of Nephrology, Sindh Institute of Urology and Transplantation, Karachi 74200, Sindh, Pakistan.
World J Transplant. 2023 Sep 18;13(5):221-238. doi: 10.5500/wjt.v13.i5.221.
The second half of the previous century witnessed a tremendous rise in the number of clinical kidney transplants worldwide. This activity was, however, accompanied by many issues and challenges. An accurate diagnosis and appropriate management of causes of graft dysfunction were and still are, a big challenge. Kidney allograft biopsy played a vital role in addressing the above challenge. However, its interpretation was not standardized for many years until, in 1991, the Banff process was started to fill this void. Thereafter, regular Banff meetings took place every 2 years for the past 30 years. Marked changes have taken place in the interpretation of kidney allograft biopsies, diagnosis, and classification of rejection and other non-rejection pathologies from the original Banff 93 classification. This review attempts to summarize those changes for increasing the awareness and understanding of kidney allograft pathology through the eyes of the Banff process. It will interest the transplant surgeons, physicians, pathologists, and allied professionals associated with the care of kidney transplant patients.
上世纪下半叶,全球临床肾移植数量大幅增长。然而,这一活动伴随着诸多问题和挑战。准确诊断并妥善处理移植物功能障碍的病因,过去是、现在仍然是一项巨大的挑战。同种异体肾移植活检在应对上述挑战中发挥了至关重要的作用。然而,多年来其解读一直未标准化,直到1991年启动了班夫进程来填补这一空白。此后,在过去30年里,每两年定期召开一次班夫会议。从最初的班夫93分类开始,同种异体肾移植活检的解读、排斥反应及其他非排斥性病理的诊断和分类都发生了显著变化。本综述试图通过班夫进程来总结这些变化,以提高对同种异体肾移植病理学的认识和理解。它将引起与肾移植患者护理相关的移植外科医生、内科医生、病理学家及相关专业人员的兴趣。