Cohn J N
Postgrad Med J. 1986 Jun;62(728):599-600. doi: 10.1136/pgmj.62.728.599.
Vasoconstriction increases impedance to ventricular ejection and impairs the performance of the dilated myopathic heart. Vasodilator drug therapy by reducing vascular resistance, increasing vascular compliance and increasing vascular capacitance improves cardiac function and relieves the signs and symptoms of congestive heart failure. Earlier intervention in an attempt to alter the natural history of cardiomyopathy should be studied.
血管收缩会增加心室射血的阻力，并损害扩张型心肌病心脏的功能。血管扩张剂药物治疗通过降低血管阻力、增加血管顺应性和增加血管容量来改善心脏功能，并缓解充血性心力衰竭的体征和症状。应该研究早期干预以试图改变心肌病自然病程的情况。
