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肺移植中食管功能和反流评估:美国 UNOS 认证移植中心的全国性调查。

Esophageal Function and Reflux Evaluations in Lung Transplantation: A Nationwide Survey of UNOS-Accredited Transplant Centers in the United States.

机构信息

Division of Gastroenterology, Hepatology and Endoscopy, Brigham and Women's Hospital, Boston, Massachusetts, USA.

LKS Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China.

出版信息

Clin Transl Gastroenterol. 2023 Dec 1;14(12):e00641. doi: 10.14309/ctg.0000000000000641.

DOI:10.14309/ctg.0000000000000641
PMID:37747103
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10749699/
Abstract

INTRODUCTION

Gastroesophageal reflux disease has been associated with worse lung transplant outcomes. We aimed to assess local practices for esophageal function testing (EFT) across transplant centers.

METHODS

This was a survey study of all United Network for Organ Sharing-accredited adult lung transplant centers regarding local EFT practice.

RESULTS

Among 39/63 (60%) responded centers, 38.5% required any EFT (35.9% esophageal manometry, 15.4% pH monitoring, and 28.2% pH impedance), while another 28.2% may consider EFT based on symptoms. Five-year transplant volume was higher among centers requiring EFT (253 vs 159, P = 0.04).

DISCUSSION

Only a minority of lung transplant centers routinely obtained EFT, supporting the need for guidelines for standardized reflux/esophageal assessment.

摘要

简介

胃食管反流病与肺移植预后较差有关。我们旨在评估移植中心之间食管功能测试(EFT)的当地实践情况。

方法

这是一项针对所有获得联合器官共享网络认证的成人肺移植中心的调查研究,旨在了解当地 EFT 实践情况。

结果

在 63 个有回应的中心中,有 39 个(60%)中心需要进行任何 EFT(35.9%食管测压,15.4% pH 监测,28.2% pH 阻抗),而另外 28.2%中心可能根据症状考虑进行 EFT。需要 EFT 的中心的 5 年移植量更高(253 例与 159 例,P = 0.04)。

讨论

只有少数肺移植中心常规进行 EFT,这支持制定标准化反流/食管评估指南的必要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8a03/10749699/f0ad88ad6472/ct9-14-e00641-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8a03/10749699/f0ad88ad6472/ct9-14-e00641-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8a03/10749699/f0ad88ad6472/ct9-14-e00641-g001.jpg

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