Tianjin Union Medical Center, 190 Jieyuan Road. Hongqiao District, Tianjin, 300121, China.
Eur Spine J. 2023 Nov;32(11):4020-4029. doi: 10.1007/s00586-023-07940-w. Epub 2023 Sep 25.
Adult degenerative scoliosis (ADS) is a 3D deformity that greatly affects the quality of life of patients and is closely related to the quality of paraspinal muscles (PSMs), but the specific degenerative characteristics have not been described.
This study included ADS patients who were first diagnosed in our hospital from 2018 to 2022. Muscle volume (MV) and fat infiltration (FI) of PSM were measured by 3D reconstruction, and spinal parameters were assessed by X-ray. The values of convex side (CV) and concave side (CC) were compared.
Fifty patients were enrolled with a mean age of 64.1 ± 5.8 years old. There were significant differences in MV, FI, and Cobb angle between male and female groups. The MV of MF and PS on the CC was significantly larger than that on the CV. In the apex and the segments above the apex, the FI of the MF on the CC is greater than the CV, and in the CV of the segment below the apex, the FI of the MF is greater than the CC. Besides, there was a significant positive correlation between the FI and Cobb angle in the MF of the CC-CV.
There were significant differences in the MV and FI of PSM on both sides of the spine in ADS patients. It was determined that the PSM of ADS showed different degrees of degeneration in different levels of the lumbar spine and were positively correlated with Cobb angle.
成人退变性脊柱侧凸(ADS)是一种三维畸形,极大地影响了患者的生活质量,与脊柱旁肌肉(PSM)的质量密切相关,但具体的退行性特征尚未描述。
本研究纳入了 2018 年至 2022 年在我院首次诊断为 ADS 的患者。通过 3D 重建测量 PSM 的肌肉体积(MV)和脂肪浸润(FI),并通过 X 射线评估脊柱参数。比较凸侧(CV)和凹侧(CC)的值。
共纳入 50 例患者,平均年龄 64.1±5.8 岁。男女组间 MV、FI 和 Cobb 角存在显著差异。CC 上 MF 和 PS 的 MV 明显大于 CV。在顶点和顶点上方的节段,CC 上 MF 的 FI 大于 CV,在顶点下方的 CV 节段,MF 的 FI 大于 CC。此外,CC-CV 上 MF 的 FI 与 Cobb 角之间存在显著正相关。
ADS 患者脊柱两侧的 PSM 的 MV 和 FI 存在显著差异。确定 ADS 的 PSM 在腰椎的不同水平显示出不同程度的退化,并且与 Cobb 角呈正相关。