Di Girolamo A, Di Girolamo M, Cini C, Coccia R, De Marco C
Physiol Chem Phys Med NMR. 1986;18(1):33-6.
Thialysine resistant CHO cells utilize thialysine added to the culture medium to a lesser extent than the parental cells. Thialysine is utilized in protein synthesis and it is incorporated into proteins in place of lysine. The parental strain substitutes up to 11% of protein lysine by thialysine, while variant cells substitute a maximum of 5% of protein lysine.