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本文引用的文献

1
Characteristics of cardiac involvement in immune-mediated necrotizing myopathy.免疫介导性坏死性肌病的心脏受累特征。
Front Immunol. 2023 Feb 28;14:1094611. doi: 10.3389/fimmu.2023.1094611. eCollection 2023.
2
Anti-SRP immune-mediated necrotizing myopathy: A critical review of current concepts.抗信号识别颗粒免疫介导的坏死性肌病：对当前概念的批判性回顾。
Front Immunol. 2022 Oct 13;13:1019972. doi: 10.3389/fimmu.2022.1019972. eCollection 2022.
3
Immunotherapy reversed myopathy but not cardiomyopathy in a necrotizing autoimmune myopathy patient with positive anti-SRP and MDA-5 autoantibodies.免疫疗法逆转了坏死性自身免疫性肌病伴抗 SRP 和 MDA-5 自身抗体阳性患者的肌病，但未逆转心肌病。
BMC Cardiovasc Disord. 2021 Feb 12;21(1):88. doi: 10.1186/s12872-021-01900-2.
4
Secondary cardiac involvement in anti-SRP-antibody-positive myopathy: an 87-year-old woman with heart failure symptoms as the first clinical presentation.抗信号识别颗粒抗体阳性肌病的心脏继发性受累：以心力衰竭症状为首发表现的 87 岁女性。
BMC Neurol. 2020 Jan 17;20(1):29. doi: 10.1186/s12883-020-1599-5.
5
Anti-signal Recognition Particle Antibody-positive Necrotizing Myopathy with Secondary Cardiomyopathy: The First Myocardial Biopsy- and Multimodal Imaging-proven Case.抗信号识别颗粒抗体阳性坏死性肌病伴继发性心肌病：首例经心肌活检和多模态影像学证实的病例
Intern Med. 2019 Nov 1;58(21):3189-3194. doi: 10.2169/internalmedicine.2564-18. Epub 2019 Jul 10.
6
Cardiac Manifestations in Idiopathic Inflammatory Myopathies: An Overview.特发性炎性肌病的心脏表现：综述
Cardiol Rev. 2019 May/Jun;27(3):131-137. doi: 10.1097/CRD.0000000000000241.
7
Autoimmune Myopathies: Updates on Evaluation and Treatment.自身免疫性肌病：评估与治疗的最新进展。
Neurotherapeutics. 2018 Oct;15(4):976-994. doi: 10.1007/s13311-018-00676-2.
8
Immune-Mediated Necrotizing Myopathy.免疫介导性坏死性肌病。
Curr Rheumatol Rep. 2018 Mar 26;20(4):21. doi: 10.1007/s11926-018-0732-6.
9
Intravenous Immune Globulin for Statin-Triggered Autoimmune Myopathy.静脉注射免疫球蛋白治疗他汀类药物引发的自身免疫性肌病。
N Engl J Med. 2015 Oct 22;373(17):1680-2. doi: 10.1056/NEJMc1506163.
10
Inflammatory myopathy with anti-signal recognition particle antibodies: case series of 100 patients.伴有抗信号识别颗粒抗体的炎性肌病：100例患者的病例系列
Orphanet J Rare Dis. 2015 May 13;10:61. doi: 10.1186/s13023-015-0277-y.

坏死性自身免疫性肌病（NAM）患者心脏受累的证据。

Evidence of Cardiac Involvement in a Patient With Necrotizing Autoimmune Myopathy (NAM).

作者信息

Khan Omair A, Wilches Rita M, Mehrabi Joseph N, Tanji Kurenai, Konka Sarita

机构信息

Internal Medicine, Maimonides Medical Center, New York, USA.

Resident Physician, Maimonides Medical Center, New York, USA.

出版信息

Cureus. 2023 Aug 25;15(8):e44106. doi: 10.7759/cureus.44106. eCollection 2023 Aug.

DOI:10.7759/cureus.44106
PMID:37750137
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10518158/
Abstract

Necrotizing autoimmune myopathy (NAM) is a rare inflammatory myopathy primarily affecting skeletal muscles. Cardiac involvement has been reported in immune-mediated necrotizing myopathy (IMNM), but its extent remains poorly understood. We present a unique case of a 68-year-old male with anti-signal recognition particle (SRP) antibody-positive NAM initially presenting with elevated troponin levels. Our case demonstrates cardiac involvement as the presenting feature of NAM, which is a unique feature of inflammatory myopathy.

摘要

坏死性自身免疫性肌病（NAM）是一种罕见的炎性肌病，主要累及骨骼肌。免疫介导的坏死性肌病（IMNM）中已有心脏受累的报道，但其程度仍知之甚少。我们报告了一例独特的病例，一名68岁男性，抗信号识别颗粒（SRP）抗体阳性的NAM，最初表现为肌钙蛋白水平升高。我们的病例显示心脏受累是NAM的首发特征，这是炎性肌病的一个独特特征。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4a5f/10518158/70122dd2429b/cureus-0015-00000044106-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4a5f/10518158/21cebc146e4c/cureus-0015-00000044106-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4a5f/10518158/70122dd2429b/cureus-0015-00000044106-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4a5f/10518158/21cebc146e4c/cureus-0015-00000044106-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4a5f/10518158/70122dd2429b/cureus-0015-00000044106-i02.jpg