Bartolini A, Borneto B, Gasparetto B, Ruffinengo U
Riv Neurol. 1986 Mar-Apr;56(2):75-81.
43 patients with a cerebral supratentorial tumor and an increased uptake at the static scan underwent intravenous radionuclide angiography with time-activity curve analysis. The increased uptake was evident during radionuclide angiography in about 50% of the cases, 16% during the upslope and 40% during the downslope of the curve. From these data it was concluded that increased uptake in tumours is determined rather than by an increased blood flow by the barrier disruption which may be operative in determining the increased uptake during the first pass in about 40% of the cases. In this case thy typical modification of the curve is characterized by a decreased falling rate of the downslope.
43例幕上脑肿瘤患者在静态扫描时摄取增加，接受了静脉放射性核素血管造影并进行了时间-活性曲线分析。在放射性核素血管造影期间，约50%的病例摄取增加明显，其中16%在曲线上升段，40%在曲线下降段。从这些数据得出结论，肿瘤摄取增加不是由血流增加决定的，而是由屏障破坏决定的，屏障破坏在约40%的病例首次通过时可能起作用决定摄取增加。在这种情况下，曲线的典型改变表现为下降段下降速率降低。
