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白细胞计数、血小板计数、红细胞沉降率和C反应蛋白对败血症和心内膜炎的诊断有用吗?

Are white blood cell count, platelet count, erythrocyte sedimentation rate and C-reactive protein useful in the diagnosis of septicaemia and endocarditis?

作者信息

Hellgren U, Julander I

出版信息

Scand J Infect Dis. 1986;18(5):487-8. doi: 10.3109/00365548609032370.

DOI:10.3109/00365548609032370
PMID:3775277
Abstract

In 851 predominantly adult patients with septicaemia or endocarditis data regarding white blood cell (WBC) count, platelet count, ESR and C-reactive protein (CRP) obtained within 3 days of admission were analyzed retrospectively. Among 232 patients with complete laboratory data none had the combination of normal ESR, negative CRP and lack of both leukocytosis and thrombocytopenia. CRP was positive (greater than 10 mg/l) in 93%, ESR was elevated (greater than 20 mm/h) in 90%, leukocytosis (WBC greater than 9 X 10(9)/l) was present in 60% and thrombocytopenia (platelets less than 150 X 10(9)/l) in 35% of the patients. Patients with pneumococcal infection had generally higher ESR and CRP values and WBC counts than patients with other infections.

摘要

对851例主要为成年败血症或心内膜炎患者入院3天内获得的白细胞(WBC)计数、血小板计数、血沉(ESR)和C反应蛋白(CRP)数据进行回顾性分析。在232例有完整实验室数据的患者中,无一例血沉正常、C反应蛋白阴性且无白细胞增多和血小板减少同时存在的情况。93%的患者CRP呈阳性(大于10mg/l),90%的患者血沉升高(大于20mm/h),60%的患者有白细胞增多(WBC大于9×10⁹/l),35%的患者有血小板减少(血小板小于150×10⁹/l)。肺炎球菌感染患者的血沉、CRP值和白细胞计数通常高于其他感染患者。

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Extension of antimicrobial treatment in patients with left-sided native valve endocarditis based on elevated C-reactive protein values.基于C反应蛋白值升高对左侧自体瓣膜心内膜炎患者延长抗菌治疗时间
Eur J Clin Microbiol Infect Dis. 2007 Aug;26(8):587-90. doi: 10.1007/s10096-007-0319-z.
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Septicemia and endocarditis, 1965-1980, in a Swedish university hospital for infectious diseases.
1965年至1980年期间,在瑞典一家大学传染病医院发生的败血症和心内膜炎情况。
Infection. 1987 May-Jun;15(3):177-83. doi: 10.1007/BF01646043.
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Malaria prophylaxis.疟疾预防
Br Med J (Clin Res Ed). 1988 May 28;296(6635):1536-7. doi: 10.1136/bmj.296.6635.1536-c.
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Clinical implications of positive blood cultures.血培养阳性的临床意义。
Clin Microbiol Rev. 1989 Oct;2(4):329-53. doi: 10.1128/CMR.2.4.329.