Dwiyana Reiva Farah, Tsaqilah Laila, Sukesi Lilik, Avriyanti Erda, Suhada Kamelia Utami, Zahira Nazya Irene
Department of Dermatology and Venereology, Faculty of Medicine, Universitas Padjadjaran-Dr. Hasan Sadikin Hospital, Bandung, West Java, Indonesia.
Department of Internal Medicine, Faculty of Medicine, Universitas Padjadjaran-Dr. Hasan Sadikin Hospital, Bandung, West Java, Indonesia.
Clin Cosmet Investig Dermatol. 2023 Sep 21;16:2613-2621. doi: 10.2147/CCID.S418776. eCollection 2023.
This study aims to delineate the demographic and clinical characteristics of xerosis, pruritus, and pallor among patients with stage 5 chronic kidney disease (CKD) undergoing hemodialysis at Dr. Hasan Sadikin General Hospital, Bandung.
This cross-sectional, descriptive study involved the analysis of 139 selected medical records of patients with stage 5 CKD who underwent hemodialysis between July and August 2022. A comprehensive examination was conducted by a dermatovenereologist, and the findings were duly recorded in the patients' medical records. The documentation encompassed gender, age, employment status, as well as the clinical characteristics of xerosis, pruritus, and pallor. The collected data were analyzed using descriptive statistical methods.
Out of the 139 patients, 70 (50.4%) were male, while 69 (49.6%) were female. The mean (SD) age was 47.6 (11.8) years. The majority of the patients were unemployed (n=96, 69.1%). The median (IQR) duration of hemodialysis was 48 (96.0-24.0) months. The predominant findings were xerosis (n=84, 60.4%) and pallor (n=83, 59.7%), followed by pruritus (n=56, 40.3%). Instances of xerosis were more frequently observed in males, whereas pallor was more prevalent in females. Xerosis and pruritus exhibited higher prevalence in the ≥65 years age group, whereas pallor was more common in the 18-44 years age group. In contrast to xerosis, pruritus and pallor were more frequently noted in the unemployed group. Xerosis was predominantly mild with overall dry skin (ODS) score of one, and it was mainly observed on the patients' legs. Among those experiencing pruritus, over half displayed a moderate severity with visual analogue scale (VAS) scores ranging from ≥3 to <7. Patients with pallor mostly exhibited hemoglobin levels below 10 g/dL.
Xerosis, pruritus, and pallor were prevalent among patients with stage 5 CKD undergoing hemodialysis. These disorders presented with distinct demographic and clinical characteristics. Timely diagnosis and intervention have the potential to enhance the quality of life for these patients.
本研究旨在描述万隆哈桑·萨迪金综合医院接受血液透析的5期慢性肾脏病（CKD）患者中皮肤干燥、瘙痒和面色苍白的人口统计学和临床特征。
本横断面描述性研究分析了2022年7月至8月期间接受血液透析的139例5期CKD患者的选定病历。由皮肤性病科医生进行全面检查，并将检查结果妥善记录在患者病历中。记录内容包括性别、年龄、就业状况，以及皮肤干燥、瘙痒和面色苍白的临床特征。使用描述性统计方法对收集的数据进行分析。
139例患者中，70例（50.4%）为男性，69例（49.6%）为女性。平均（标准差）年龄为47.6（11.8）岁。大多数患者失业（n=96，69.1%）。血液透析的中位（四分位间距）时长为48（96.0 - 24.0）个月。主要表现为皮肤干燥（n=84，60.4%）和面色苍白（n=83，59.7%），其次是瘙痒（n=56，40.3%）。皮肤干燥在男性中更常见，而面色苍白在女性中更普遍。皮肤干燥和瘙痒在≥65岁年龄组中患病率较高，而面色苍白在18 - 44岁年龄组中更常见。与皮肤干燥不同，瘙痒和面色苍白在失业组中更常见。皮肤干燥主要为轻度，总体皮肤干燥（ODS）评分为1分，主要出现在患者腿部。在有瘙痒症状的患者中，超过一半表现为中度严重程度，视觉模拟量表（VAS）评分≥3至<7。面色苍白的患者大多血红蛋白水平低于10 g/dL。
皮肤干燥、瘙痒和面色苍白在接受血液透析的5期CKD患者中普遍存在。这些病症呈现出不同的人口统计学和临床特征。及时诊断和干预有可能提高这些患者的生活质量。
