Nessim Kostandy Erini, Wan David, Imseis Essam
Department of Pediatrics, Division of Gastroenterology, The University of Texas Health Science Center at Houston, Houston, TX.
Department of Diagnostic and Interventional Imaging, McGovern Medical School, University of Texas, Houston, TX.
ACG Case Rep J. 2023 Sep 23;10(9):e01158. doi: 10.14309/crj.0000000000001158. eCollection 2023 Sep.
Post-transplant lymphoproliferative disorder is a complication in organ transplant recipients characterized by uncontrolled proliferation of B-lymphocytes, occurring in 6% of pediatric patients, with risk factors including primary Epstein-Barr virus infection, intensity of immunosuppression, and cytomegalovirus infection. The clinical symptoms are often nonspecific, and it is associated with a high mortality rate if left untreated. We describe a rare case of post-transplant lymphoproliferative disorder who presented with pleural-based masses resulting in pleural effusions.
移植后淋巴细胞增生性疾病是器官移植受者的一种并发症，其特征为B淋巴细胞不受控制地增殖，在6%的儿科患者中出现，危险因素包括原发性EB病毒感染、免疫抑制强度和巨细胞病毒感染。临床症状通常不具有特异性，如果不治疗，死亡率很高。我们描述了一例罕见的移植后淋巴细胞增生性疾病病例，该病例表现为以胸膜为基底的肿块并导致胸腔积液。
