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内射频治疗化脓性汗腺炎的疗效和安全性。

The efficacy and safety of endo-radiofrequency for the treatment of hidradenitis suppurativa.

机构信息

Department of Dermatology, Rasool Akram Medical Complex Clinical Research Development Center (RCRDC), School of Medicine, Iran University of Medical Sciences (IUMS), Tehran, Iran.

Tehran University of Medical Sciences, Tehran, Iran.

出版信息

Skin Res Technol. 2023 Sep;29(9):e13450. doi: 10.1111/srt.13450.

Abstract

BACKGROUND

Hidradenitis suppurativa (HS) is a chronic and recurrent disease of the axilla and groin with inflammatory lesions. There is no definitive medication or intervention to cure the disease. Radiofrequency (RF) is a modality to destroy the lesions by transferring heat into the skin. To date, few studies have been conducted to evaluate the efficacy and safety of RF at HS.

METHODS

This 9-month, prospective, nonrandomized, and single-blinded study is a clinical trial conducted in 10 patients with refractory HS. In all patients, the initial grade of HS was evaluated. The procedure involved treating HS of the axilla with a endo-RF wave device. Post-treatment evaluation included: determination of the severity of the disease by a blinded dermatologist, the degree of patient satisfaction, tolerability in each patient, and complications of the procedure. We also evaluate the recurrence of the disease during a 6-month follow-up.

RESULTS

The satisfaction level after the intervention among under-studied cases was excellent and good in six of cases. There was a significant difference in comparing the grading score of patients before and 3 months after receiving RF (P-value: 0.01). Regarding tolerability, eight of the patients could tolerate it. We had no complication after the intervention and four cases had not recurrence during a 6-month follow-up.

CONCLUSION

Endo-RF is an effective and safe modality for treating HS however to prevent the recurrence, periodic therapy sessions are needed.

摘要

背景

化脓性汗腺炎(HS)是一种发生在腋窝和腹股沟的慢性复发性炎症性疾病。目前尚无根治该病的药物或干预措施。射频(RF)是一种通过将热量传递到皮肤中来破坏病变的方法。迄今为止,很少有研究评估 RF 在 HS 中的疗效和安全性。

方法

这是一项为期 9 个月的前瞻性、非随机、单盲临床试验,在 10 例难治性 HS 患者中进行。所有患者均对 HS 的初始分级进行了评估。该过程包括使用endo-RF 波设备治疗腋窝 HS。治疗后评估包括:由盲法皮肤科医生确定疾病严重程度、患者满意度程度、每位患者的耐受性以及手术并发症。我们还评估了 6 个月随访期间疾病的复发情况。

结果

在研究的病例中,6 例患者的干预后满意度水平为优秀和良好。与接受 RF 治疗前相比,患者的分级评分在 3 个月后有显著差异(P 值:0.01)。关于耐受性,有 8 例患者可以耐受。干预后我们没有出现并发症,4 例在 6 个月随访期间没有复发。

结论

endo-RF 是治疗 HS 的一种有效且安全的方法,但为了预防复发,需要定期进行治疗。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a866/10462799/a7550d8217be/SRT-29-e13450-g002.jpg

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