Cavallari Strozze Catharin Virgínia Maria, Zutin Tereza Laís Menegucci, Guiguer Elen Landgraf, Cressoni Araújo Adriano, Fornari Laurindo Lucas, Chagas Eduardo F Baisi, Gasparotti Zorzetto Cássia Fernanda, Bueno Patrícia C Dos Santos, Dos Santos Bueno Manoela, Cervelim Nunes Yandra, Cavallari Strozze Catharin Vitor, Gonzaga Heron Fernando, Barbalho Sandra Maria
Department of Biochemistry and Pharmacology, School of Medicine, University of Marília (UNIMAR), Avenida Hygino Muzzy Filho, 1001, Marília 17525-902, São Paulo, Brazil.
Postgraduate Program in Structural and Functional Interactions in Rehabilitation, University of Marília (UNIMAR), Avenida Hygino Muzzy Filho, 1001, Marília 17525-902, São Paulo, Brazil.
Diseases. 2023 Aug 30;11(3):113. doi: 10.3390/diseases11030113.
COVID-19 has generated a scenario for global health with multiple systemic impairments. This retrospective study evaluated the clinical, radiological, and pulmonary functional evolution in 302 post-COVID-19 patients. Regarding post-COVID-19 pulmonary symptoms, dry cough, dyspnea, and chest pain were the most frequent. Of the associated comorbidities, asthma was more frequent (23.5%). Chest tomography (CT) initially showed a mean pulmonary involvement of 69.7%, and evaluation in the subsequent months showed improvement in the evolutionary image. With less than six months post-pathology, there was a commitment of 37.7% from six to twelve months it was 20%, and after 12 months it was 9.9%. As for most of the sample, 50.3% of the patients presented CT normalization less than six months after infection, 23% were normalized between six and twelve months, and 5.2% presented with normalized images after twelve months, with one remaining. A percentage of 17.3% maintained post-COVID-19 pulmonary residual sequelae. Regarding spirometry, less than six months after pathology, 59.3% of the patients presented regular exam results, 12.3% had their function normalized within six to twelve months, and 6.3% had normal exam results twelve months after their post-pathology evaluation. Only 3.6% of the patients still showed some alteration during this period.
新冠病毒病（COVID-19）引发了一种出现多种全身功能障碍的全球健康状况。这项回顾性研究评估了302例COVID-19康复患者的临床、影像学和肺功能演变情况。关于COVID-19后的肺部症状，干咳、呼吸困难和胸痛最为常见。在相关合并症中，哮喘更为常见（23.5%）。胸部断层扫描（CT）最初显示肺部平均受累率为69.7%，随后几个月的评估显示影像学表现有所改善。发病后不到6个月时，受累率为37.7%；6至12个月时为20%；12个月后为9.9%。对于大多数样本，50.3%的患者在感染后不到6个月时CT表现恢复正常，23%在6至12个月之间恢复正常，5.2%在12个月后图像恢复正常，另有1例未恢复。17.3%的患者存在COVID-19后的肺部残留后遗症。关于肺量计检查，发病后不到6个月时，59.3%的患者检查结果正常，12.3%的患者在6至12个月内肺功能恢复正常，6.3%的患者在发病后12个月的检查结果正常。在此期间，只有3.6%的患者仍有一些异常表现。
