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采用覆盖瓣技术联合富含血小板血浆并在空气填塞下治疗的色素性视网膜炎患者的单侧黄斑裂孔

UNILATERAL MACULAR HOLE IN A PATIENT WITH RETINITIS PIGMENTOSA TREATED WITH COVER FLAP TECHNIQUE WITH THE USE OF PLATELET-RICH PLASMA UNDER AIR TAMPONADE.

作者信息

Lo Giudice Gregorio, Alessandria Amedeo, Imburgia Aurelio, Anastasi Marco, Randazzo Viviana, Masaniello Filippo, Pioppo Antonino

机构信息

Ophthalmic Unit, Department Head and Neck, ARNAS-Civico, Palermo, Italy.

Ophthalmic Unit, University of Galati, Galati, Romania.

出版信息

Retin Cases Brief Rep. 2025 Jan 1;19(1):84-90. doi: 10.1097/ICB.0000000000001491. Epub 2024 Dec 13.

Abstract

PURPOSE

The purpose of the study is to show the excellent anatomical result of the inverted flap-assisted technique with platelet-rich plasma under air for retinitis pigmentosa complicated with macular hole.

METHODS

A 32-year-old woman, previously diagnosed with retinitis pigmentosa, was referred to our department complaining of decreased central vision in her left eye for 4 weeks. At the time of presentation, the optical coherence tomography and fundoscopy examination showed the presence of a macular hole of 620 μ m in diameter. The closure of the macular hole was observed after the surgical procedure, but endophthalmitis occurred 5 days, postoperatively.

RESULTS

In our presented case, the cover flap-assisted technique with platelet-rich plasma under air for retinitis pigmentosa complicated with macular hole resulted in excellent anatomical outcomes with unremarkable visual recovery.

CONCLUSION

The physiopathology of full-thickness macular holes in retinitis pigmentosa patients remains still not fully elucidated. Pars plana vitrectomy with the adjunct of highly concentrated pure platelet-rich plasma have shown successful results.

摘要

目的

本研究的目的是展示在空气中使用富含血小板血浆的反转瓣辅助技术治疗色素性视网膜炎合并黄斑裂孔的优异解剖学结果。

方法

一名32岁女性,先前被诊断为色素性视网膜炎,因左眼中心视力下降4周前来我院就诊。就诊时,光学相干断层扫描和眼底镜检查显示存在直径为620μm的黄斑裂孔。手术过程后观察到黄斑裂孔闭合,但术后5天发生了眼内炎。

结果

在我们展示的病例中,在空气中使用富含血小板血浆的覆盖瓣辅助技术治疗色素性视网膜炎合并黄斑裂孔,取得了优异的解剖学结果,但视力恢复不明显。

结论

色素性视网膜炎患者全层黄斑裂孔的病理生理学仍未完全阐明。玻璃体切除术联合高浓度纯富含血小板血浆已显示出成功的结果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d4a7/11649180/032c2a03cd66/cabr-19-084-g001.jpg

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