Nogawa K, Tsuritani I, Yamada Y, Kido T, Honda R, Ishizaki M, Kurihara T
Toxicol Lett. 1986 Sep;32(3):283-8. doi: 10.1016/0378-4274(86)90120-7.
Sister-chromatid exchanges (SCEs) were analyzed from peripheral lymphocyte cultures of 8 men and 16 women who had been exposed to environmental cadmium (Cd), and 6 controls. Average Cd concentrations in blood of the Cd-polluted group were 8.9 micrograms/l for men and 10.0 micrograms/l for women. These were no significant differences in SCE rates between the Cd-polluted and nonpolluted groups. There were no significant correlations between SCE rates and blood or urinary Cd concentrations. Cadmium alone may be an insignificant agent in producing chromosomal damage to peripheral blood lymphocytes.
对8名接触环境镉（Cd）的男性和16名女性以及6名对照者的外周血淋巴细胞培养物进行了姐妹染色单体交换（SCE）分析。镉污染组男性血液中镉的平均浓度为8.9微克/升，女性为10.0微克/升。镉污染组和未污染组之间的SCE率没有显著差异。SCE率与血液或尿液中的镉浓度之间没有显著相关性。仅镉可能是对外周血淋巴细胞产生染色体损伤的一种无关紧要的因素。
