1Virginia Veterinary Centers, Midlothian, VA.
2Department of Veterinary Medicine and Surgery, College of Veterinary Medicine, University of Missouri, Columbia, MO.
J Am Vet Med Assoc. 2023 Sep 27;262(1):117-124. doi: 10.2460/javma.23.07.0387. Print 2024 Jan 1.
To describe a novel scoring system of feline pigmented iris lesions prior to utilization of diode laser ablation of progressive pigmented iris lesions and to retrospectively evaluate short- and long-term patient outcomes following transcorneal diode laser ablation.
317 client-owned cats (356 eyes) were included.
Records of cats undergoing diode laser ablation from January 2000 to December 2018 were retrospectively reviewed. A novel clinical grading system to describe severity of feline iris hyperpigmentation was developed. Recorded parameters included signalment, operated-upon eye, presurgical iris pigmentation score, intraocular pressure, visual status, postoperative complications, repeat laser surgery, patient status at last follow-up, time to death, and presumptive or known cause of death.
Complications included corneal ulceration (25/356 [7%]), glaucoma (18/356 [5%]), uveitis (4/356 [1.1%]), and corneal edema (3/356 [0.8%]). Enucleation was performed in 12 eyes due to blindness and secondary glaucoma. Repeat laser due to continued progression of pigment was performed in 18.5% of eyes. Two study patients were euthanized due to presumptive metastatic disease. Of the 250 cats for whom confirmation was available via phone call or medical records, 240 (96%) were alive at 1 year.
Diode laser ablation appears safe overall and may be effective in decreasing progression of feline iris pigmentation. Complication risks appear minimal.
描述一种新型猫色素性虹膜病变评分系统，用于二极管激光消融进行性色素性虹膜病变之前，并回顾性评估经角膜二极管激光消融后短期和长期的患者结局。
共纳入 317 只患宠猫（356 只眼）。
回顾性分析了 2000 年 1 月至 2018 年 12 月间接受二极管激光消融的猫的记录。开发了一种新的临床分级系统来描述猫虹膜过度色素沉着的严重程度。记录的参数包括品种、手术眼、术前虹膜色素沉着评分、眼内压、视力状况、术后并发症、重复激光手术、最后一次随访时的患者状况、死亡时间以及死亡的假定或已知原因。
并发症包括角膜溃疡（25/356[7%]）、青光眼（18/356[5%]）、葡萄膜炎（4/356[1.1%]）和角膜水肿（3/356[0.8%]）。由于失明和继发青光眼，12 只眼进行了眼球摘除。由于色素持续进展，18.5%的眼需要重复激光治疗。由于疑似转移性疾病，2 只研究患猫被安乐死。通过电话或病历确认的 250 只猫中，240 只（96%）在 1 年内存活。
二极管激光消融总体上看起来安全，可能有效减少猫虹膜色素沉着的进展。并发症风险似乎很小。
