Department of Pediatrics, Hematology and Oncology, Medical University of Gdańsk, ul. Skłodowskiej-Curie 3A, 80-210 Gdańsk.
Department of Pediatrics, Hematology and Oncology, Medical University of Gdańsk, ul. Skłodowskiej-Curie 3A, 80-210 Gdańsk.
Immunol Allergy Clin North Am. 2023 Nov;43(4):665-679. doi: 10.1016/j.iac.2023.04.001. Epub 2023 May 19.
To a large extent, the clinical picture of pediatric mastocytosis depends on the age at which it is diagnosed. A neonate with diffuse cutaneous mastocytosis may frequently present in a severe state requiring treatment. Toddlers may require long-term anti-mediator therapy, and this may lead to concerns such as organizing preschool education due to the need for epinephrine injections. A teenager may have to face cutaneous disease persistence or a diagnosis of systemic mastocytosis. Further studies are needed to refine the available treatment options and prognosis for different age groups.
在很大程度上，儿科肥大细胞瘤的临床特征取决于其诊断时的年龄。患有弥漫性皮肤肥大细胞瘤的新生儿可能经常处于严重状态，需要治疗。幼儿可能需要长期的抗介质治疗，这可能会导致一些问题，如由于需要注射肾上腺素而需要组织学前教育。青少年可能不得不面对皮肤疾病的持续存在或系统性肥大细胞瘤的诊断。需要进一步的研究来完善不同年龄组的可用治疗选择和预后。
