Eising Heleen P, Punt Marieke C, Schermer Tjard, Leemans Jaklien C, Bongers Marlies Y
Department of Gynaecology and Obstetrics, Gelre Hospital, Apeldoorn, The Netherlands.
Grow Research School Oncology and Reproduction, Maastricht University, Maastricht, The Netherlands.
Haemophilia. 2023 Nov;29(6):1573-1579. doi: 10.1111/hae.14872. Epub 2023 Sep 27.
The International Society on Thrombosis and Haemostasis bleeding assessment tool (ISTH-BAT), is used during the diagnostic workup of bleeding disorders. Data on ISTH-BAT scores in women with heavy menstrual bleeding (HMB) undergoing endometrial ablation (EA) could be essential in optimizing HMB counselling.
To investigate the postsurgical incidence of amenorrhea, dysmenorrhea, quality of life, re-intervention after EA, and ISTH-BAT score.
This study included women who have undergone EA because of HMB. During a follow-up of 2 to 5 years, ISTH-BAT, pictorial blood assessment chart (PBAC), and Short Form-36 survey (SF-36) were administered. At 10 years of follow-up surgical re-interventions were evaluated.
Seventy-one women were included of whom 77% (n = 55) had an ISTH-BAT score < 6, versus 23% (n = 16) ISTH-BAT score ≥6 (mean age 46.3 versus 42.3, p = 0.004). In the ISTH-BAT ≥6 group versus < 6 group, amenorrhea occurred in 63% (10/16) versus 82% (45/55) (p = 0.111), dysmenorrhea in 38% (6/16) versus 18% (10/55) (p = 0.111), and surgical re-intervention in 19% (3/16) versus 25% (14/55) (p = 0.582). SF-36 item (Bodily) pain was lower in the ISTH-BAT ≥6 group versus < 6 (median score 58.7 vs. 80.0, p = 0.104).
An ISTH-BAT score ≥6 may be related to a lower amenorrhea incidence and higher dysmenorrhea rate after EA.
国际血栓与止血学会出血评估工具（ISTH-BAT）用于出血性疾病的诊断检查。对于接受子宫内膜消融术（EA）的月经过多（HMB）女性，ISTH-BAT评分数据对于优化HMB咨询可能至关重要。
研究EA术后闭经、痛经的发生率、生活质量、EA术后再次干预情况以及ISTH-BAT评分。
本研究纳入因HMB接受EA的女性。在2至5年的随访期间，使用ISTH-BAT、图像化失血评估图（PBAC）和简明健康状况调查量表（SF-36）进行评估。在随访10年时评估手术再次干预情况。
纳入71名女性，其中77%（n = 55）的ISTH-BAT评分为<6，23%（n = 16）的ISTH-BAT评分≥6（平均年龄46.3岁对42.3岁，p = 0.004）。在ISTH-BAT≥6组与<6组中，闭经发生率分别为63%（10/16）对82%（45/55）（p = 0.111），痛经发生率分别为38%（6/16）对18%（10/55）（p = 0.111），手术再次干预率分别为19%（3/16）对25%（14/55）（p = 0.582）。ISTH-BAT≥6组的SF-36项目（身体）疼痛评分低于<6组（中位数评分58.7对80.0，p = 0.104）。
ISTH-BAT评分≥6可能与EA术后较低的闭经发生率和较高的痛经发生率相关。
