Loberg Matthew A, Tigue Megan L, Gallant Jean-Nicolas, Wang Huiying, Canberk Sule, Weiss Vivian L
Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
Otolaryngology-Head and Neck Surgery, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
Cytopathology. 2024 Jan;35(1):60-69. doi: 10.1111/cyt.13311. Epub 2023 Sep 27.
The guidelines for the workup of thyroid nodules have been established in adult populations and secondarily applied to paediatric populations. In particular, The Bethesda System for Reporting Thyroid Cytopathology (TBSRTC) is commonly applied to both adult and paediatric thyroid nodules. However, as paediatric nodules have distinct molecular drivers and behavioural trajectories, there is renewed interest in diagnostic and management strategies that are paediatric specific. Here, we review key differences between paediatric and adult thyroid cancer and recent literature evaluating the use of TBSRTC in paediatric populations.
甲状腺结节检查的指南已在成人中确立,并继而应用于儿科人群。特别是,甲状腺细胞病理学报告的贝塞斯达系统(TBSRTC)通常适用于成人和儿科甲状腺结节。然而,由于儿科结节具有独特的分子驱动因素和行为轨迹,人们对针对儿科的诊断和管理策略重新产生了兴趣。在此,我们回顾儿科和成人甲状腺癌之间的关键差异,以及评估TBSRTC在儿科人群中应用的近期文献。