伴有PD-L1和SSTR2a表达的肝EB病毒相关炎性假瘤样滤泡树突状细胞肉瘤侵袭性变异型

Aggressive Variant of Hepatic Epstein-Barr Virus-Associated Inflammatory Pseudotumor-like Follicular Dendritic Cell Sarcoma with PD-L1 and SSTR2a Expression.

作者信息

Pardasani Madhur, Rajakannu Muthukumarassamy, Vij Mukul, Rajalingam Rajesh, Rela Mohamed

机构信息

Rela Institute & Medical Centre, Chennai 6000044, India.

出版信息

Diagnostics (Basel). 2023 Sep 12;13(18):2916. doi: 10.3390/diagnostics13182916.

DOI:10.3390/diagnostics13182916

PMID:37761283

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10529831/

Abstract

An aggressive Epstein-Barr virus (EBV)-associated inflammatory pseudotumor-like follicular dendritic cell (IPT-like FDC) sarcoma is reported in an adult female. The patient developed multifocal recurrence and passed away 13 months after the initial surgical resection. A bright field microscopic examination of the tumor demonstrated a classical growth pattern and the diffuse expression of Programmed death ligand 1 (PD-L1) and somatostatin receptor 2a (SSTR2a).

摘要

据报道，一名成年女性患有侵袭性爱泼斯坦-巴尔病毒（EBV）相关的炎性假瘤样滤泡树突状细胞（IPT样FDC）肉瘤。该患者出现多灶性复发，并在初次手术切除后13个月去世。肿瘤的明视野显微镜检查显示出典型的生长模式以及程序性死亡配体1（PD-L1）和生长抑素受体2a（SSTR2a）的弥漫性表达。